Role of viruses in periodontitis:An extensive review of herpesviruses,human immunodeficiency virus,coronavirus-19,papillomavirus and hepatitis viruses  

作　　者：Mohammed Khalid Mahmood Mohammed Taib Fatih Handren Ameer Kurda Nwsiba Khalid Mahmood Farman Uthman Shareef Hemin Faraidun Herve Tassery Delphine Tardivo Romain Lan Zana Fuad Noori Balen Hamid Qadir Arman Dlshad Hassan 

机构地区：[1]Aix-Marseille University,CNRS,EFS,ADES,Marseille 13000,France [2]College of Dentistry,Komar University of Science and technology,Sulaimani 46001,Iraq [3]College of Dentistry,Sulaimani University,Sulaimani 46001,Iraq [4]Department of Biology,College of Science,Sulaimani University,Sulaimani 46001,Iraq [5]Department of Medical Laboratory Science,College of Science,Charmo University,Chamchamal/Sulaimani 46001,Iraq [6]Department of Biology,University of Freiburg,Mina Biotech,Freiburg 79098,Germany [7]Department of Odontology,Timone Hospital,Aix Marseille University,APHM,Marseille 13000,France,LBN Laboratory,Montpellier 34000,France [8]Department of Odontology,Timone Hospital,Aix Marseille University,APHM,CNRS,EFS,ADES,Marseille 13000,France [9]Department of Dentistry,American University of Sulaimani Iraq AUIS,Sulaimani 46001,Iraq [10]Department of Biomedical Science,University of Denver,Denver,CO 80014,United States

出　　处：《World Journal of Virology》2024年第4期7-23,共17页世界病毒学杂志（英文）

摘　　要：Periodontitis is the inflammation of the supporting structures around the dentition.Several microbial agents,mostly bacteria,have been identified as causative factors for periodontal disease.On the other hand,oral cavity is a rich reservoir for viruses since it contains a wide variety of cell types that can be targeted by viruses.Traditionally,the focus of research about the oral flora has been on bacteria because the most widespread oral diseases,like periodontitis and dental caries,are outcomes of bacterial infection.However,recently and especially after the emergence of coronavirus disease 2019,there is a growing tendency toward including viruses also into the scope of oral microbiome investigations.The global high prevalence of periodontitis and viral infections may point out to a concomitant or synergistic effect between the two.Although the exact nature of the mechanism still is not clearly understood,this could be speculated through the manipulation of the immune system by viruses;hence facilitating the furthermore colonization of the oral tissues by bacteria.This review provides an extensive and detailed update on the role of the most common viruses including herpes family(herpes simplex,varicella-zoster,Epstein-Barr,cytomegalovirus),Human papillomaviruses,Human immunodeficiency virus and severe acute respiratory syndrome coronavirus 2 in the initiation,progression and prognosis of periodontitis.

关 键 词：Virus PERIODONTITIS Bacteria HERPESVIRUS Herpes simplex virus Varicella-zoster virus Epstein-Barr virus CYTOMEGALOVIRUS Human papillomaviruses SARS-CoV-2 Human immunodeficiency virus 

分 类 号：R512.91[医药卫生—内科学]