supported by the National Natural Science Foundation of China(32071443);China Postdoctoral Science Foundation(2023M731465);the Natural Science Foundation of Gansu province(23JRRA1134)。
The emergence of drug resistance to virus(i.e.,acyclovir(ACV)to herpesviruses)has been termed one of the common clinical issues,emphasizing the discovery of new antiviral agents.To address it,a genome-wide clustered r...
Periodontitis is the inflammation of the supporting structures around the dentition.Several microbial agents,mostly bacteria,have been identified as causative factors for periodontal disease.On the other hand,oral cav...
supported by the Natural Science Foundation of Beijing Municipality(L222074);Key R&D Program of Shandong Province,China(2019JZZY011011).
Dear Editor,Patients undergoing allogeneic hematopoietic stem cell transplantation(HSCT)often experience a significant reduction in immune function due to factors such as severe lymphopenia,immunosuppressive treatment...
financially supported by the Science and Technology Commission of Shanghai Municipality(21ZR1427200).
Carassius auratus herpesvirus(CaHV)is a pathogen isolated from crucian carp(Carassius auratus)associated with high mortality.A diagnosis method that can detect the virus at an early stage,specifically and accurately,i...
supported by grants from the National Key R&D Plan of the Ministry of Science and Technology,China(2023YFD2400201,2022YFF1000302);the Strategic Pilot Science and Technology of the Chinese Academy of Sciences Project(XDA24030203).
Frequent outbreaks of emerging infectious diseases in fish,such as Carassius auratus herpesvirus(CaHV)infection has caused great economic losses in China.However,the lack of a sensitive cell culture system has limited...
Background: Primary effusion lymphoma (PEL) is a lymphoid proliferation related to Kaposi sarcoma herpesvirus 8/human herpesvirus 8 (KSHV/HHV8) that affects mainly human immunodeficiency virus (HIV) infected individua...
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24030203 and XDA24030104);National Key Research and Development Program of China(2018YFD0900504);National Natural Science Foundation of China(32073009)and the Youth Innovation Promotion Association provided funding to Shun Li.National Natural Science Foundation of China provided funding to Long-Feng Lu under grant number 32173023.National Natural Science Foundation of China provided funding to Dan-Dan Chen under grant number 32002431.
Control of host autophagy acceleration or attenuation has been confirmed in multiple terrestrial animal viruses.Little is known about such mechanisms in aquatic viruses.Here,we report a selective and ingenious autopha...
supported by the National Natural Science Foundation of China(U21A20260);the Natural Science Foundation of Henan Province(212300410359);the Independent innovation project of Henan Academy of Agricultural Sciences(2022ZC65);the BBSRC Newton Fund Joint Centre Awards on“UK-China Centre of Excellence for Research on Avian Diseases”(BBS/OS/NW/000007)。
Over the past two decades, numerous non-coding RNAs(ncRNAs) have been identified in different biological systems including virology, especially in large DNA viruses such as herpesviruses. As a representative oncogenic...
Research of YY and HWF is supported by grants from the Special Research Fund of Ghent University(CSC-cofunding grant and Concerted Research Action GOA013-17).
TypeⅢinterferons(IFNs)represent the most recently discovered group of IFNs.Together with typeⅠIFNs(e.g.IFN-α/β),typeⅢIFNs(IFN-λ)are produced as part of the innate immune response to virus infection,and elicit an...
This project was supported by the National Eye Institute/National Institutes of Health core grant P30-EY06360(Department of Ophthalmology,Emory University School of Medicine);National Eye Institute of the National Institutes of Health under award RO1 EY029594(SY);The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the views or policies of the Department of Health and Human Services,nor does mention of trade names,commercial products,or organizations imply endorsement by the U.S.Government;This research was also supported an unrestricted departmental grant from Research to Prevent Blindness,Inc.to the Emory Eye Center,Emory University School of Medicine and Association for Research in Vision and Ophthalmology Mallinckrodt Young Investigator Award(SY).
Acute retinal necrosis(ARN)is a devastating syndrome characterized by panuveitis,retinal necrosis,and a high rate of retinal detachment that may result in poor visual outcomes if not promptly diagnosed and treated.ARN...