supported by the National Natural Science Foundation of China(32071443);China Postdoctoral Science Foundation(2023M731465);the Natural Science Foundation of Gansu province(23JRRA1134)。
The emergence of drug resistance to virus(i.e.,acyclovir(ACV)to herpesviruses)has been termed one of the common clinical issues,emphasizing the discovery of new antiviral agents.To address it,a genome-wide clustered r...
Periodontitis is the inflammation of the supporting structures around the dentition.Several microbial agents,mostly bacteria,have been identified as causative factors for periodontal disease.On the other hand,oral cav...
supported by grants from the NationalKey Research and Development Program of China(2022YFC3400900);Chinese Postdoctoral Science Foundation(GZB20230886,2023M743998);Natural Science Foundationof China(82030046 to M.S.Z,82070329 and 32241028 toZ.L.);the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2019BT02Y198);Guangdong Science and Technology Department(2020B1212030004).
Human herpesviruses(HHV),including the alpha,beta,andgamma subfamilies,are enveloped viruses with broad prevalence,establishing life-time latent infections and inducing a variety of diseases[1].Among them,herpes simpl...
Research of YY and HWF is supported by grants from the Special Research Fund of Ghent University(CSC-cofunding grant and Concerted Research Action GOA013-17).
TypeⅢinterferons(IFNs)represent the most recently discovered group of IFNs.Together with typeⅠIFNs(e.g.IFN-α/β),typeⅢIFNs(IFN-λ)are produced as part of the innate immune response to virus infection,and elicit an...
Objective To investigate herpesvirus infection in early stage of hematopoietic stem cell transplantation(HSCT)by multiplex polymerase chain reaction(PCR),and to explore the association between multiple herpesviruses i...
the Ministry of Science and Technology(National Key R&D Program of China,No.2016YFA0502101);the National Natural Science Foundation of China(No.81630059 and 81325012).
Many viruses,enveloped or non-enveloped,remodel host membrane structures for their replication,assembly and escape from host cells.Herpesviruses are important human pathogens and cause many diseases.As large enveloped...
supported by grants from the Natural Science Foundation for Distinguished Young Scholars (81425017);the Ministry of Science and Technology of China (2016YFA0502100);the Key Project of the Natural Science Foundation of China (81230037);the National Institutes of Health (1R01AI116442) to KL;the Natural Science Foundation of China (81620108021) to MHL
This special issue of the journal is dedicated to the recent research progress on human herpesviruses(HHVs).Human herpesviruses are distributed worldwide,and more than 90%of adults are infected by one or multiple HHVs...
supported by the National Natural Science Foundations of China (81372139, 31670171, 81728011);the National Key Research and Development Program of China (2017YFC1200204);the Hunan Provincial Natural Science Foundation of China (2015JJ2149)
Herpesviruses are remarkable pathogens that have evolved multiple mechanisms to evade host immunity, ensuring their proliferation and egress. Among these mechanisms, herpesviruses utilize elaborate extracellular vesic...
supported by the National Natural Science Foundation of China(81471930,81402542);the National Basic Research Program of China(973 Program)(2012CB519001);the National Key Research and Development Program of China(2016YFC1200400)
The cell membrane regulates many physiological processes including cellular communication,homing and metabolism. It is therefore not surprising that the composition of the host cell membrane is manipulated by intracel...
The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact ...