HERPESVIRUSES

作品数:16被引量:62H指数:4
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相关领域:医药卫生农业科学更多>>
相关期刊:《Cellular & Molecular Immunology》《Science China(Life Sciences)》《Virologica Sinica》《China Medical Abstracts(Internal Medicine)》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Genome-wide CRISPR screens identify CLC-2 as a drug target for anti-herpesvirus therapy:tackling herpesvirus drug resistance
《Science China(Life Sciences)》2025年第2期515-526,共12页Fayu Yang Nan Wei Shuo Cai Jing Liu Qingping Lan Hao Zhang Lu Shang Bo Zheng Mi Wang Yingchun Liu Lifang Zhang Chenzhong Fei Wu Tong Changlong Liu Ersheng Kuang Guangzhi Tong Feng Gu 
supported by the National Natural Science Foundation of China(32071443);China Postdoctoral Science Foundation(2023M731465);the Natural Science Foundation of Gansu province(23JRRA1134)。
The emergence of drug resistance to virus(i.e.,acyclovir(ACV)to herpesviruses)has been termed one of the common clinical issues,emphasizing the discovery of new antiviral agents.To address it,a genome-wide clustered r...
关键词:HERPESVIRUSES CRISPR host-directed therapy CLC-2 DIDS 
Role of viruses in periodontitis:An extensive review of herpesviruses,human immunodeficiency virus,coronavirus-19,papillomavirus and hepatitis viruses
《World Journal of Virology》2024年第4期7-23,共17页Mohammed Khalid Mahmood Mohammed Taib Fatih Handren Ameer Kurda Nwsiba Khalid Mahmood Farman Uthman Shareef Hemin Faraidun Herve Tassery Delphine Tardivo Romain Lan Zana Fuad Noori Balen Hamid Qadir Arman Dlshad Hassan 
Periodontitis is the inflammation of the supporting structures around the dentition.Several microbial agents,mostly bacteria,have been identified as causative factors for periodontal disease.On the other hand,oral cav...
关键词:Virus PERIODONTITIS Bacteria HERPESVIRUS Herpes simplex virus Varicella-zoster virus Epstein-Barr virus CYTOMEGALOVIRUS Human papillomaviruses SARS-CoV-2 Human immunodeficiency virus 
The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses
《hLife》2024年第3期141-146,共6页Cong Sun Jia-Wen Yang Chu Xie Xin-Yan Fang Guo-Long Bu Ge-Xin Zhao Dan-Ling Dai Zheng Liu Mu-Sheng Zeng 
supported by grants from the NationalKey Research and Development Program of China(2022YFC3400900);Chinese Postdoctoral Science Foundation(GZB20230886,2023M743998);Natural Science Foundationof China(82030046 to M.S.Z,82070329 and 32241028 toZ.L.);the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2019BT02Y198);Guangdong Science and Technology Department(2020B1212030004).
Human herpesviruses(HHV),including the alpha,beta,andgamma subfamilies,are enveloped viruses with broad prevalence,establishing life-time latent infections and inducing a variety of diseases[1].Among them,herpes simpl...
关键词:diseases neutral ENVELOPE 
Herpesviruses and the TypeⅢInterferon System被引量:2
《Virologica Sinica》2021年第4期577-587,共11页Yue Yin Herman W.Favoreel 
Research of YY and HWF is supported by grants from the Special Research Fund of Ghent University(CSC-cofunding grant and Concerted Research Action GOA013-17).
TypeⅢinterferons(IFNs)represent the most recently discovered group of IFNs.Together with typeⅠIFNs(e.g.IFN-α/β),typeⅢIFNs(IFN-λ)are produced as part of the innate immune response to virus infection,and elicit an...
关键词:TypeⅢinterferon(IFN-λ) HERPESVIRUS Innate immunity Herpes simplex virus(HSV) 
Application of multiplex PCR assay to study early multiple herpesviruses infection during HSCT
《China Medical Abstracts(Internal Medicine)》2019年第3期178-179,共2页JI Yuhan 
Objective To investigate herpesvirus infection in early stage of hematopoietic stem cell transplantation(HSCT)by multiplex polymerase chain reaction(PCR),and to explore the association between multiple herpesviruses i...
关键词:INFECTION ANEMIA DISEASES 
Remodeling of host membranes during herpesvirus assembly and egress被引量:1
《Protein & Cell》2019年第5期315-326,共12页Ying Lv Sheng Zhou Shengyan Gao Hongyu Deng 
the Ministry of Science and Technology(National Key R&D Program of China,No.2016YFA0502101);the National Natural Science Foundation of China(No.81630059 and 81325012).
Many viruses,enveloped or non-enveloped,remodel host membrane structures for their replication,assembly and escape from host cells.Herpesviruses are important human pathogens and cause many diseases.As large enveloped...
关键词:HERPESVIRUSES assembly EGRESS BUDDING fusion MEMBRANE deformations 
Herpesviruses: epidemiology, pathogenesis, and interventions被引量:8
《Virologica Sinica》2017年第5期347-348,共2页Ke Lan Min-Hua Luo 
supported by grants from the Natural Science Foundation for Distinguished Young Scholars (81425017);the Ministry of Science and Technology of China (2016YFA0502100);the Key Project of the Natural Science Foundation of China (81230037);the National Institutes of Health (1R01AI116442) to KL;the Natural Science Foundation of China (81620108021) to MHL
This special issue of the journal is dedicated to the recent research progress on human herpesviruses(HHVs).Human herpesviruses are distributed worldwide,and more than 90%of adults are infected by one or multiple HHVs...
关键词:simplex PATHOGENESIS HERPES EPIDEMIOLOGY infected spherical dedicated replication INTERFERON ZOSTER 
Extracellular vesicles: novel vehicles in herpesvirus infection被引量:4
《Virologica Sinica》2017年第5期349-356,共8页Lingzhi Liu Quan Zhou Yan Xie Lielian Zuo Fanxiu Zhu Jianhong Lu 
supported by the National Natural Science Foundations of China (81372139, 31670171, 81728011);the National Key Research and Development Program of China (2017YFC1200204);the Hunan Provincial Natural Science Foundation of China (2015JJ2149)
Herpesviruses are remarkable pathogens that have evolved multiple mechanisms to evade host immunity, ensuring their proliferation and egress. Among these mechanisms, herpesviruses utilize elaborate extracellular vesic...
关键词:HERPESVIRUSES extracellular vesicles(EVs) INFECTION PATHOGENESIS 
Manipulation of the host cell membrane by humanγ-herpesviruses EBV and KSHV for pathogenesis被引量:2
《Virologica Sinica》2016年第5期395-405,共11页Fang Wei Qing Zhu Ling Ding Qing Liang Qiliang Cai 
supported by the National Natural Science Foundation of China(81471930,81402542);the National Basic Research Program of China(973 Program)(2012CB519001);the National Key Research and Development Program of China(2016YFC1200400)
The cell membrane regulates many physiological processes including cellular communication,homing and metabolism. It is therefore not surprising that the composition of the host cell membrane is manipulated by intracel...
关键词:cell membrane remodeling Epstein-Barr virus(EBV) Kaposi’s sarcoma-associated herpesvirus(KSHV) 
Regulation of Wnt/β-catenin signaling by herpesviruses被引量:3
《World Journal of Virology》2016年第4期144-154,共11页Kevin J Zwezdaryk Joseph A Combs Cindy A Morris Deborah E Sullivan 
The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact ...
关键词:HERPESVIRUS Herpes simplex virus-1 VARICELLA zoster VIRUS Cytomegalovirus Epstein-Barr VIRUS Kaposi’s sarcoma-associated HERPESVIRUS WNT/Β-CATENIN Glycogen synthase kinase-3 AXIN 
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