supported by the National Natural Science Foundation of China(92369104,82271790,92169113);the Beijing Natural Science Foundation(JQ23028,7212067);the National Key R&D Program of China(2021YFA1300202,2022YFC2302900);the Strategic Priority Research Programs of the Chinese Academy of Sciences(XDB29020000);the Key Research Program of Frontier Sciences of Chinese Academy of Sciences(ZDBS-LY-SM025);the CAS Project for Young Scientists in Basic Research(YSBR-010);the Fok Ying Tung Education Foundation to P.X.,the Youth Innovation Promotion Association of CAS to S.W.
Inflammasomes play important roles in resisting infections caused by various pathogens.HSV-1 is a highly contagious virus among humans.The process by which HSV-1 particles bud from the nucleus is unique to herpes viru...
supported by the Scientific and Technological Innovation Project of the Laoshan Laboratory(No.LSKJ202203700);the Beijing Natural Science Foundation(No.8232026).
Jellyfish blooms are increasingly prevalent coastal phenomena,with Aurelia coerulea being a significant contributor.The complex life history of jellyfish,featuring a sessile polyp stage,is a key factor in bloom format...
This book is mainly compiled for adolescents and falls into five parts.It tells the author's growth experiences,days with his family members,feelings about life,and encouragement for adolescents.Young readers will gai...
supported by Shandong Shunfeng BiotechnologyCo.Ltd.,Jinan,China.
Of the more than 370000 species of higher plants in nature,fewer than 0.1%can be geneticallymodified due to limitations of the current gene delivery systems.Even for those that can be genetically modified,the modifica...
We acknowledge Dr.Bo Zhang(Wuhan Institute of Virology)and Dr.Heinz Feldmann(National Institutes of Health,Hamilton,Montana,USA)for providing the Ebola cDNA and minigenome assay system,respectively;This research is supported by grants from the National Natural Science Foundation of China(81825015);National Key R&D Program of China(2017YFA0505801);National Science and Technology Major Project(2018ZX10101004);National Natural Science Foundation of China(81871650 and 31630086);The Natural Science Foundation of Hubei Province Innovation Group(2017CFA022);Advanced Customer Cultivation Project of Wuhan National Biosafety Laboratory(2019ACCP-MS06).
Ebola virus(EBOV)is an enveloped negative-sense RNA virus and a member of the filovirus family.Nucleoprotein(NP)expression alone leads to the formation of inclusion bodies(IBs),which are critical for viral RNA synthes...
supported by grants from the National Natural Science Foundation of China(81974503 and 81871095);the National Key R&D Program of China(2018YFC2000304);the Key International S&T Cooperation Program of China(2016YFE0113700);the European Union’s Horizon 2020 Research and Innovation Program(633589);the Natural Science Foundation of Beijing,China(7202096);the Tsinghua University independent research program(7191007,China)。
Although primary vesical calculi is an ancient disease,the mechanism of calculi formation remains unclear.In this study,we established a novel primary vesical calculi model with D,L-choline tartrate in mice.Compared w...
Tourists admire cherry blossoms on the Wuhan University campus in Wuhan,Hubei Province in central China,on March 8.The campus,one of the best places to enjoy the sight in China,opened reservations that day for visitor...
The pursuit of health has always been the driving force for the advancement of human society,and social development will be profoundly affected by every breakthrough in the medical industry.With the arrival of the inf...
Supported by Shanghai Shenkang Hospital Development Center Three-Year Action Plan for Difficult Diseases Precision Treatment Project,No.16CR2022A;Pudong New Area Joint Research Project,No.PW2017D-1;hanghai Shenkang Hospital Development Center Technology Joint Promotion Project,No.SHDC12016236;Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Training fund,No.PYMDT-003
BACKGROUND Tumor budding,is a promising prognostic hallmark in many cancers,and can help us better assess the degree of malignancy in gastric cancer(GC)and in colorectal cancer.In the past few years,several articles o...
Infectious Diseases of Poverty is an open access,peer-reviewed journal publishing topic areas and methods that address essential public health questions relating to infectious diseases of poverty.These include various...