financed by the National Natural Science Foundation of China(No.81970571);the Natural Science Foundation of Chongqing Municipality,China(No.CSTB2022NSCQ-MSX1001);the Program for Youth Innovation in Future Medicine,Chongqing Medical University(No.W0109).
MAFB is essential for regulating male-type urethral differentiation,and especially,its variation can contribute to hypospadias in mice.However,the potential mechanism is still unclear.Here we observed that the basic l...
supported by grants from the National Natural Science Foundation of China(81974503 and 81871095);the National Key R&D Program of China(2018YFC2000304);the Key International S&T Cooperation Program of China(2016YFE0113700);the European Union’s Horizon 2020 Research and Innovation Program(633589);the Natural Science Foundation of Beijing,China(7202096);the Tsinghua University independent research program(7191007,China)。
Although primary vesical calculi is an ancient disease,the mechanism of calculi formation remains unclear.In this study,we established a novel primary vesical calculi model with D,L-choline tartrate in mice.Compared w...
The aim of this work is to emphasize the importance of a differential diagnosis of von Brunn’s nests in cats from other urothelial neoplastic disorders, as transitional cell carcinoma, for a subsequent optimal care. ...
In human nephrolithiasis, most stones are containing calcium and are located within urinary cavities; they may contain monohydrate calcium oxalate, dihydrate calcium oxalate and/or calcium phosphates in various propor...
Hemorrhagic cystitis (HC) affects a significant number of patients undergoing cyclophosphamide (CP) chemotherapy despite treatment with 2-mercaptoethane sulfonate (Mesna) to inactivate the metabolite acrolein. While t...
This work was supported by the grants from the National Natural Science Foundation of China (No. 81070555) and the Major Program of Clinical High and New Technology Research of Hospital.
Background Efficient cell adhesion and proliferation is a central issue in cell-based tissue engineering, which offers great promise for repair of urethral defects or strictures. This study evaluated the adhesion and ...
supported by grants from the National Natural Sciences Foundation of China (No. 30200284, No. 30600278, No. 30772359);Program for New Century Excellent Talents in University (NCET-06-0641);Scientific Research Foundation for the Returned Overseas Chinese Scholars (2008889)
The optimal antisense accessible sites (AAS) of uroplakin Ⅱ (UP Ⅱ ) mRNA, a specific gene expressed in bladder urothelium, were selected in order to provide a novel method for targeted therapy of transitional ce...
Project supported by the National Natural Science Foundation of China (Grant Nos. 19634020 and 19874074).
Asymmetric unit membrane (AUM) was isolated and purified from the urothelium of rabbit urinary bladder. The electron micrographs were taken from negatively stained AUM patches. The Fourier filtering and lattice distor...