This research was supported by Ministry of Science and Technology of China(MoST 2022YFC2303700 and 2021YFA1301900);National Natural Science Foundation of China(NSFC 32222040 and 32070049);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Action(TSBICIP-KJGG-008);the 1.3.5 Project for Disciplines Excellence of West China Hospital,Sichuan University(ZYYC21006)to Z.S.The pCAG-OSF vector plasmid was a kind gift from Prof.Jinbiao Ma at Fudan University。
Respiratory syncytial virus(RSV)is a nonsegmented,negative strand RNA virus that has caused severe lower respiratory tract infections of high mortality rates in infants and the elderly,yet no effective vaccine or anti...
This work was financially supported by the NYUAD COVID-19 Facilitator Research Fund from NYU Abu Dhabi,UAE.The authors acknowledge the donors and nurses for their contributions to blood donation and collection.Additionally,the authors acknowledge the technical support from the Core Technology Platforms at NYU Abu Dhabi,especially the help of Mr.Vijay Dhanvi and Mr.Jinumon Govindan.The authors also thank Dr.Ayoub Glia for the discussions.
Immunoglobulin M(IgM)and immunoglobulin G(IgG)antibodies are important biomarkers used for the diagnosis and screening of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infections in both symptomatic and a...
supported financially by the Science and Technology Development Fund(STDF),Egypt;Project No.43834.
Background:Population-based studies on the determinants of COVID-19 seroprevalence constitute a cornerstone in guiding appropriate preventive measures.Such studies are scarce in Egypt,thus we conducted this study to e...
We acknowledge Dr.Bo Zhang(Wuhan Institute of Virology)and Dr.Heinz Feldmann(National Institutes of Health,Hamilton,Montana,USA)for providing the Ebola cDNA and minigenome assay system,respectively;This research is supported by grants from the National Natural Science Foundation of China(81825015);National Key R&D Program of China(2017YFA0505801);National Science and Technology Major Project(2018ZX10101004);National Natural Science Foundation of China(81871650 and 31630086);The Natural Science Foundation of Hubei Province Innovation Group(2017CFA022);Advanced Customer Cultivation Project of Wuhan National Biosafety Laboratory(2019ACCP-MS06).
Ebola virus(EBOV)is an enveloped negative-sense RNA virus and a member of the filovirus family.Nucleoprotein(NP)expression alone leads to the formation of inclusion bodies(IBs),which are critical for viral RNA synthes...
supported by the National Natural Science Foundation of China(32041002 to D.G.and 31800151 to J.W.);Guangdong Province‘Pearl River Talent Plan’Innovation and Entrepreneurship Team Project(2019ZT08Y464 to C.L.);Shenzhen Science and Technology Program(JSGG20200225150431472 and KQTD20180411143323605 to D.G.,GXWD20201231165807008 and 20200825183117001 to J.W.).
Dear Editor,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a novel emerging coronavirus that has spread worldwide since breaking out in late 2019 and has led to hundreds of millions of infections an...
the National Institute of General Medical Sciences of the National Institutes of Health under Award,No.U54GM128729.
BACKGROUND During the peak of the coronavirus diseases 2019(COVID-19)pandemic,clinicians actively studied the utility of various epidemiologic-clinical parameters to determine the prognosis for patients hospitalized w...
supported by the National Key Research and Development Program of China(2017YFD0201206);the WIV “One-Three-Five”strategic program(Y602111SA1 to XS)。
Autographa californica multiple nucleopolyhedrovirus(Ac MNPV)orf13(ac13)is a conserved gene in all sequenced alphabaculoviruses.However,its function in the viral life cycle remains unknown.In this study,we found that ...
This work was supported by grants from the National Key Research and Development Program of China(Nos.2016YFD0500301,2021YFC0863300,and 2020YFC0840900).
Background:With the ongoing worldwide coronavirus disease 2019(COVID-19)pandemic,an increasing number of viral variants are being identified,which poses a challenge for nucleic acid-based diagnostic tests.Rapid tests,...
funded in part by the Project from the Ministry of Science and Technology in China(2020YFC0841200);the National Major Science&Technology Project for Control and Prevention of Major Infectious Diseases in China(2017ZX10103004);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2020HY320001);the non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2019PT310029);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2016-I2M-1-014).
The outbreak of coronavirus disease 2019(COVID-19)in Wuhan,China,was caused by a novel coronavirus(CoV),named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).The rapid detection of viral nucleic acids is c...