Funding from Scientific Research Project of Hunan Provincial Education Department:to Investigate the Mechanism of Blood-activating Circulation Through the Regulation of Blood Stasis and Detoxification based on Wntβ-catenin Signaling Pathway(No.21B0398)Study on the Epithelial Mesenchymal Transformation of Human Umbilical Vein Endothelial Cells Induced by Fuxin Formula(No.22C0190);Changsha City 2020 Annual Guiding Science and Technology Plan Projects:Effect of Blood Circulation and Detoxification Method on Epithelial Barrier Composition and Function of Oral Mucosa(No.kzd2001010)。
OBJECTIVE:To investigate the protective effect of the Chinese herbal formula of Jiedu Huayu decoction(解毒化瘀汤,JHD)on oral mucosa of rats with oral submucosal fibrosis(OSF)and its potential mechanism of action.METHO...
This work was supported by grants from the National Key R&D Program of China(2020YFA0803402);the National Natural Science Foundation of China(#32070753,#92057204,#82088102,and#92157001);the Fundamental Research Funds for the Central Universities(#20720200069);the Project“111”sponsored by the State Bureau of Foreign Experts and Ministry of Education of China(#BP2018017);the Agilent Applications and Core Technology-University Research Grant(#4769).
When glucose is replete,mammalian/mechanistic target of rapamycin complex 1(mTORC1)is active and anchored to the lysosomal surface via the two GTPases,Ras-related GTPase(RAG)and Ras homolog enriched in brain(Rheb),whi...