云南高校图书馆联盟文献共享服务平台- ONCOGENESIS

ONCOGENESIS: 作品数：55被引量：369H指数：11; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：王建斌更多>>; 相关机构：辽宁省肿瘤医院汕头大学承德医学院附属医院南昌大学更多>>; 相关期刊：《World Journal of Biological Chemistry》《Liver Research》《Asian Journal of Andrology》《Asian Pacific Journal of Tropical Medicine》更多>>; 相关基金：国家自然科学基金江苏省科技厅科研基金河南省自然科学基金国家重点基础研究发展计划更多>>

The Role of Linker Histone Mutation in Oncogenesis: Molecular Mechanism and Structural Impact: 《BIOCELL》2025年第4期519-538,共20页Gege Liu Houfang Zhang Yunhui Peng; supported by the National Natural Science Foundation of China(No.12205112);financially supported by self-determined research funds of CCNU from the colleges’basic research and operation of MOE(CCNU24JC012);supported by Natural Science Foundation of Wuhan(No.2024040801020302).; Nucleosomes play a vital role in chromatin organization and gene regulation,acting as key hubs that inter-act with various chromatin-associated factors through diverse binding mechanisms.Recent research has highlighte...; 关键词：Linker histone H1 EPIGENETICS histone cancer mutations chromatin structure NUCLEOSOME

Attempts to restore loss of function in damaged ACD cells open the way to non-mutational oncogenesis: 《Genes & Diseases》2024年第3期5-6,共2页Vladimir F.Niculescu; This correspondence to Gene&Diseases calls attention to the controversy between proponents of genetic modification in carcinogenesis and supporters of non-mutational oncogenesis.Data from molecular cancer research and...; 关键词：RATIONAL latter finding

Small nucleolar RNA and its potential role in the oncogenesis and development of colorectal cancer被引量：2: 《World Journal of Gastroenterology》2024年第2期115-127,共13页Yang-Zheng Lan Zheng Wu Wen-Jia Chen Ze-Xuan Fang Xin-Ning Yu Hua-Tao Wu Jing Liu; the National Natural Science Foundation of China,No.82273457;Guangdong Basic and Applied Basic Research Foundation,No.2021A1515012180 and No.2023A1515012762;Special Grant for Key Area Programs of Guangdong Department of Education,No.2021ZDZX2040;and Science and Technology Special Project of Guangdong Province,No.210715216902829.; Small nucleolar RNAs(snoRNAs)represent a class of non-coding RNAs that play pivotal roles in post-transcriptional RNA processing and modification,thereby contributing significantly to the maintenance of cellular funct...; 关键词：Small nucleolar RNAs Colorectal cancer DYSREGULATION BIOMARKER

Role of inositol polyphosphate-4-phosphatase type II in oncogenesis of digestive system tumors: 《World Journal of Gastrointestinal Oncology》2023年第10期1706-1716,共11页Le Han Shuo Chen Shi-Yu Du; Inositol polyphosphate-4-phosphatase type II(INPP4B)is a newly discovered PI(3,4,5)P3 phosphatase.Many studies have revealed that INPP4B is upregulated or downregulated in tumors of the digestive system,and the abnorm...; 关键词：Inositol polyphosphate-4-phosphatase type II Tumors of the digestive system Protein kinase B Serum and glucocorticoid-regulated kinase 3

Fungal mycobiome-mediated immune response:a non-negligible promoter in pancreatic oncogenesis and chemoresistance: 《Cancer Drug Resistance》2023年第2期284-290,共7页Yaling Jiang Valentina Donati Godefridus J.Peters Elisa Giovannetti Dong Mei Deng; This work was supported by grants from the Cancer Center Amsterdam(CCA)Foundation,As-sociazione Italiana per la Ricerca sul Cancro(AIRC)and Fondazione Pisana per la Scienza(FPS)to Giovannetti E,and the Dutch Research Council(NWO)(OCENW.XS22.4.135)to Jiang Y.; Pancreatic ductal adenocarcinoma(PDAC)is one of the most lethal cancers in humans due to late diagnosis and poor response to treatments.The tumor microenvironment(TME)of PDAC is characterized by a distinctive,suppress...; 关键词：Mycobiome pancreatic cancer CHEMORESISTANCE interleukin 33 type 2 immune cells

Targeting histone deacetylases for cancer therapy: Trends and challenges被引量：8: 《Acta Pharmaceutica Sinica B》2023年第6期2425-2463,共39页Tao Liang Fengli Wang Reham M.Elhassan Yongmei Cheng Xiaolei Tang Wengang Chen Hao Fang Xuben Hou; supported by the National Natural Science Foundation of China (81874288, 82003590 and 92053105);the Natural Science Foundation of Shandong Province (ZR2020QH342, China);the Key Project of Natural Science Foundation of Anhui Province for College Scholar (2022AH051216, China);Scientific Research Project of Anhui Provincial Health Commission (AHWJ2022b005, China)。; Dysregulation of histone deacetylases(HDACs) is closely related to tumor development and progression. As promising anticancer targets, HDACs have gained a great deal of research interests and two decades of effort has...; 关键词：HDACS ONCOGENESIS Selective inhibitor Combination therapy Multitarget agent PROTAC

5’tiRNA-Pro-TGG,a novel tRNA halve,promotes oncogenesis in sessile serrated lesions and serrated pathway of colorectal cancer: 《World Journal of Gastrointestinal Oncology》2023年第6期1005-1018,共14页Xin-Yuan Wang Yu-Jie Zhou Hai-Ying Chen Jin-Nan Chen Shan-Shan Chen Hui-Min Chen Xiao-Bo Li; Supported by the Program of Health and Family Planning Research Project Plan of Pudong New Area Health Committee,No.PW2020D-12.; BACKGROUND Transfer RNA(tRNA)-derived small RNAs(tsRNAs)are small fragments that form when tRNAs severe.tRNA halves(tiRNAs),a subcategory of tsRNA,are involved in the oncogenic processes of many tumors.However,their s...; 关键词：Noncoding RNA tRNA halves Sessile serrated lesions Colon cancer Serrated pathway

Re-analysis of hepatitis B virus integration sites reveals potential new loci associated with oncogenesis in hepatocellular carcinoma被引量：1: 《World Journal of Virology》2023年第3期209-220,共12页Ryuta Kojima Shingo Nakamoto Tadayoshi Kogure Yaojia Ma Keita Ogawa Terunao Iwanaga Na Qiang Junjie Ao Ryo Nakagawa Ryosuke Muroyama Masato Nakamura Tetsuhiro Chiba Jun Kato Naoya Kato; BACKGROUND Hepatitis B virus(HBV)is a major cause of hepatocellular carcinoma(HCC).HBV DNA can get integrated into the hepatocyte genome to promote carcinogenesis.However,the precise mechanism by which the integrated ...; 关键词：CARCINOMA HEPATOCELLULAR Hepatitis B virus Virus integration

The Oncogenesis of Glial Cells in Diffuse Gliomas and Clinical Opportunities: 《Neuroscience Bulletin》2023年第3期393-408,共16页Qiyuan Zhuang Hui Yang Ying Mao; supported by the National Key Research and Development Program of China(2020YFA0804200);the National Natural Science Foundation of China(82073166,82273203);a Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);supported by the Program for Professors of Special Appointment(Eastern Scholar)at the Shanghai Institutions of Higher Learning(SSF151005);supported by the Student Scientific Research Program(Fuqing Scholar)of Shanghai Medical College,Fudan University(FQXZ202117C).; Glioma is the most common and lethal intrinsic primary tumor of the brain.Its controversial origins may contribute to its heterogeneity,creating challenges and difficulties in the development of therapies.Among the co...; 关键词：Glioma origin Stem/progenitor cell Oncometabolite Immune heterogeneity Neuron-tumor interaction

Critical roles of non-coding RNAs in lifecycle and biology of Marek's disease herpesvirus被引量：4: 《Science China(Life Sciences)》2023年第2期251-268,共18页Man Teng Zhi-Jian Zhu Yongxiu Yao Venugopal Nair Gai-Ping Zhang Jun Luo; supported by the National Natural Science Foundation of China(U21A20260);the Natural Science Foundation of Henan Province(212300410359);the Independent innovation project of Henan Academy of Agricultural Sciences(2022ZC65);the BBSRC Newton Fund Joint Centre Awards on“UK-China Centre of Excellence for Research on Avian Diseases”(BBS/OS/NW/000007)。; Over the past two decades, numerous non-coding RNAs(ncRNAs) have been identified in different biological systems including virology, especially in large DNA viruses such as herpesviruses. As a representative oncogenic...; 关键词：HERPESVIRUS MDV miRNA lincRNA circRNA CRISPR PATHOGENESIS ONCOGENESIS

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