腹式深吸气屏气技术在左侧乳腺癌改良根治术后放疗中的应用  

作　　者：陈美琴[1] 周玲[1] 丁叔波[1] 

机构地区：[1]浙江省金华市中心医院,321000

出　　处：《浙江临床医学》2024年第9期1327-1329,共3页Zhejiang Clinical Medical Journal

基　　金：金华市科学技术研究计划项目(2021-4-013,2021-4-014)。

摘　　要：目的探讨腹式深吸气屏气(ADIBH)技术在左侧乳腺癌改良根治术后内乳链放射治疗中的剂量学优势。方法纳入20例左侧乳腺癌改良根治术后需行内乳链放疗的患者,比较ADIBH和自由呼吸(FB)两种呼吸模式在逆向调强放疗(IMRT)技术中的剂量学差异,包括靶区均匀性(HI)参数,肺、心脏、冠状动脉左前降支(LAD)以及右侧乳腺剂量比较。结果ADIBH呼吸模式下心脏、LAD、左肺受照射剂量(D_(mean))较FB模式下均有明显下降(P<0.05)。结论即使包含内乳区域淋巴放疗,采用ADIBH呼吸模式下的调强放疗可以减少心脏、左侧冠状动脉和肺等重要器官的靶区照射,带来临床获益。Objective To investigate the dosimetric advantages of abdominal deep inspiration breath hold(ADIBH)technique in the treatment of left breast cancer after modified radical mastectomy,including internal mammary chain radiotherapy.Methods A total of 20 patients with left breast cancer undergoing modified radical mastectomy requiring internal mammary chain radiotherapy were selected.To compare the dosimetric differences between ADIBH and free breathing in inverse planning intensity-modulated radiation therapy(IMRT).The parameters of homogeneity index(HI)of target volume,dose comparison of lung,heart,left anterior descending coronary artery(LAD)and right breast were included.Results The mean dose to heart,left anterior descending coronary artery and left lung in ADIBH breathing mode were significantly lower than those in FB breathing mode(P<0.05).Conclusion Even with the inclusion of lymphatic radiotherapy in the internal mammary region,ADIBH can significantly reduce the exposure to vital organs such as the heart,left coronary artery,and lung,with clinical benefits.

关 键 词：乳腺癌 腹式深吸气屏气 自由呼吸 放射治疗 危及器官 

分 类 号：R737.9[医药卫生—肿瘤]