消化内镜在炎症性肠病诊治中的临床应用效果  

Clinical application effect of digestive endoscopy in the diagnosis and treatment of inflammatory bowel disease

作　　者：郑舒丹 杨柳[1] ZHENG Shudan;YANG Liu(Department of Gastroenterology,Suzhou Municipal Hospital Affiliated to Nanjing Medical University,Suzhou,Jiangsu,215000,China)

机构地区：[1]南京医科大学附属苏州市立医院消化内科,江苏苏州215000

出　　处：《当代医学》2024年第15期166-169,共4页Contemporary Medicine

摘　　要：目的探究消化内镜在炎症性肠病(IBD)诊治中的临床应用效果。方法选取2018年2月至2023年2月南京医科大学附属苏州市立医院收治的80例IBD患者作为研究对象,采用随机数字表法分为观察组与对照组,每组40例。所有患者均行消化内镜检查,对照组给予常规治疗,观察组采用消化内镜治疗。以病理学诊断结果为金标准,分析消化内镜检查的诊断准确率;比较两组临床疗效、炎症因子水平及不良反应发生率。结果80例炎症性肠病患者中,病理学诊断溃疡性结肠炎(UC)66例,消化内镜诊断UC 64例,消化内镜诊断UC的准确率为96.97%;病理学诊断克罗恩病(CD)14例,消化内镜诊断CD 12例,消化内镜诊断CD的准确率为85.71%。观察组治疗总有效率为90.00%,高于对照组的55.00%,差异有统计学意义(P<0.05);治疗4周后,两组C-反应蛋白(CRP)及白细胞介素-6(IL-6)水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义。结论消化内镜对炎症性肠病的诊断准确率较高,治疗效果显著,可减轻炎症因子水平,且安全性有保障,可用于临床诊治炎症性肠病。Objective To explore the clinical application effect of digestive endoscopy in the diagnosis and treatment of inflammatory bowel dis-ease(IBD).Methods 80 patients with IBD admitted to Suzhou Municipal Hospital affiliated to Nanjing Medical University were selected as the re-search subjects,and they were divided into the observation group and the control group according to random number table method,with 40 cases in each group.All patients underwent digestive endoscopy,the control group received conventional treatment,while the observation group were re-ceived digestive endoscopy.The diagnostic accuracy of digestive endoscopy was analyzed with the pathological diagnosis as the gold standard,and the clinical efficacy,levels of inflammatory factors and incidence of adverse reactions were compared between the two groups.Results Among 80 patients with inflammatory bowel disease,66 cases were diagnosed with ulcerative colitis(UC)by pathology,64 cases were diagnosed with UC by digestive endoscopy,and the accuracy of digestive endoscopy in the diagnosis of UC was 96.97%;14 cases were diagnosed with Crohn's disease(CD)by pathology,12 cases were diagnosed with CD by digestive endoscopy,and the accuracy of digestive endoscopy diagnosis of CD was 85.71%.The total effective rate of treatment in the observation group was 90.00%,which was higher than 55.00%in the control group,and the difference was statistically significant(P<0.05);after 4 weeks of treatment,C-reactive protein(CRP)and interleukin-6(IL-6)levels of the two groups were lower than before treatment,and the the observation group was lower than those the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reaction between the two groups.Conclusion Digestive endoscopy has high diagnos-tic accuracy and significant therapeutic effect on inflammatory bowel disease,which can reduce the level of inflammatory factors,and has guaranteed safety,which can be used in clinical diagnosis and treatmen

关 键 词：溃疡性结肠炎 克罗恩病 消化内镜 

分 类 号：R574[医药卫生—消化系统]