2014—2023年镇江市居民恶性肿瘤疾病负担趋势  

Trends in disease burdens of malignant tumors among residents in Zhenjiang City from 2014 to 2023

作　　者：秦平[1] 朱月兰 徐璐 王宏宇[1] QIN Ping;ZHU Yue-lan;XU Lu;WANG Hong-yu(Zhenjiang Center for Disease Control and Prevention,Jiangsu Zhenjiang 212000,China)

机构地区：[1]镇江市疾病预防控制中心,江苏镇江212000

出　　处：《江苏预防医学》2024年第4期445-449,共5页Jiangsu Journal of Preventive Medicine

基　　金：镇江市科技创新资金(重点研发计划—社会发展)(SH2020045)。

摘　　要：目的了解镇江市居民恶性肿瘤死亡率和疾病负担及变化趋势。方法利用2014—2023年镇江市死因监测数据,计算恶性肿瘤粗死亡率、标化死亡率、早死寿命损失年(YLLs)、YLLs率,采用平均年度变化百分比(AAPC)分析变化趋势。结果2014—2023年,镇江市因恶性肿瘤死亡73922例,年均粗死亡率为318.44/10万,标化死亡率为262.33/10万。粗死亡率和标化死亡率男性均高于女性(χ^(2)值分别为6087.30、199262.00,P值均<0.05)。总人群、男性恶性肿瘤粗死亡率呈上升趋势(AAPC分别为0.91%、1.19%),全人群、男性、女性恶性肿瘤YLLs率呈下降趋势(AAPC分别为-1.19%、-1.01%、-1.43%,P值均<0.05)。2023年死因顺位前5位恶性肿瘤依次为肺癌(占20.35%)、胃癌(占20.19%)、食道癌(占13.19%)、结直肠癌(占9.73%)、肝癌(占9.47%),合计占全部恶性肿瘤死亡的72.93%。相比2014年,肺癌全人群和男、女性YLLs率变化趋势无统计学意义(P值均>0.05),胃癌、食道癌、肝癌全人群、男、女性YLLs率均呈下降趋势(P值均<0.05),结直肠癌全人群、男性YLLs率均呈下降趋势(P值均<0.05)。结论镇江市恶性肿瘤标化死亡率和标化YLLs率均呈下降趋势,但依然处于较高水平,应重点关注肺癌和胃癌等消化系统肿瘤的综合防控。Objective To investigate the mortality and disease burden of malignant tumors and their changing trends among residents in Zhenjiang City.Methods The data pertaining to surveillance on causes of death were collected from Zhenjiang City from 2014 to 2023,and the crude mortality,standardized mortality,years of life lost due to premature death(YLLs)and YLLs rate of malignant tumors were calculated.In addition,the trends in crude mortality,standardized mortality,YLLs and YLLs rate of malignant tumors were investigated using average annual change percent(AAPC).Results A total of 73922 deaths occurred due to malignant tumors in Zhenjiang City from 2014 to 2023,with average annual crude mortality of 318.44/10~5 and standardized mortality of 262.33/10~5.The crude and standardized mortality was both higher among men than among women(χ^(2)=6087.30 and 199262.00,both P values<0.05),and the crude mortality of malignant tumors appeared a tendency towards a rise among total populations(AAPC=0.91%)and men(AAPC=1.19%)in Zhenjiang City from 2014 to 2023,while the YLLs rate appeared a tendency towards a decline among total populations(AAPC=-1.91%,P<0.05),men(AAPC=-1.01%,P<0.05)and women(AAPC=-1.43%,P<0.05).The five most deadly malignant tumors included lung cancer(20.35%),gastric cancer(20.19%),esophageal cancer(13.19%),colorectal cancer(9.73%)and liver cancer(9.47%)in Zhenjiang City in 2023,which consisted of 72.93%of all cancer-related mortality.There was no statistical significance in the trends in YLLs rates of lung cancer among total populations,men or women between 2023 and 2014(all P values>0.05),and the YLLs rate of gastric cancer,esophageal cancer and liver cancer all appeared a tendency towards a decline among total populations,men and women(all P values<0.05),while the YLLs rate of colorectal cancer appeared a tendency towards a decline among total populations and men(both P values<0.05).Conclusions The standardized mortality and YLLs rate of malignant tumors appeared a tendency towards a decline in Zhenjiang City from

关 键 词：恶性肿瘤 疾病负担 死亡率 早死寿命损失 

分 类 号：R73-31[医药卫生—肿瘤]