江苏省40~69岁居民胃癌发生影响因素分析  

Risk factors of gastric cancer among residents at ages of 40 to 69 years in Jiangsu Province

作　　者：陆凤安 刘付东[1] 孟显峰[2] 吴玲玲 缪伟刚 周金意[3] 罗鹏飞[3] LU Feng-an;LIU Fu-dong;MENG Xian-feng;WU Ling-ling;MIU Wei-gang;ZHOU Jin-yi;LUO Peng-fei(Yancheng Municipal Center for Disease Control and Prevention,Jiangsu Yancheng 224000,China;不详)

机构地区：[1]盐城市疾病预防控制中心,江苏盐城224000 [2]潍坊市疾病预防控制中心 [3]江苏省疾病预防控制中心

出　　处：《江苏预防医学》2024年第4期450-452,共3页Jiangsu Journal of Preventive Medicine

基　　金：盐城市医学科技发展计划项目(YK2021033);中国消化道早癌医师共同成长计划科研项目(GTCZ-2020-JS-32-0002)。

摘　　要：目的了解江苏省胃癌发生的影响因素,为有效开展胃癌防治工作提供理论依据。方法纳入2017—2022年“江苏省农村上消化道癌早诊早治”项目中19491名40~69岁居民作为调查对象,运用倾向性评分匹配对病例组和对照组进行1∶4匹配。匹配后进行单因素分析,利用logistic回归方法分析胃癌的影响因素。结果最终纳入研究1295例,病例组259例,对照组1036例。单因素分析结果显示:两组间年龄、BMI、高血压、饮酒和胃肠炎史等差异均有统计学意义(P值均<0.05)。多因素logistic回归分析显示:胃癌的危险因素为高龄(OR=2.22,95%CI:1.66~2.97)、超重(OR=1.75,95%CI:1.02~2.97)、高血压(OR=1.60,95%CI:1.19~2.15)、饮酒(OR=1.50,95%CI:1.07~2.08)和胃肠炎史(OR=1.56,95%CI:1.03~2.36)。结论应针对高龄、超重、饮酒、高血压和胃肠炎等危险因素采取有效防控措施,以降低胃癌的患病风险。Objective To investigate the risk factors of gastric cancer in Jiangsu Province,so as to provide insights into gastric cancer prevention and control.Methods A total of 19491 residents at ages of 40 to 69 years included in the Early Diagnosis and Early Treatment Projects for Upper Gastrointestinal Cancer in Jiangsu Province from 2017 to 2022 were recruited,and the case and control groups were matched at a ratio of 1:4 using propensity score matching.Univariate analysis was performed following matching,and the risk factors of gastric cancer were identified using multivariate logistic regression analysis.Results A total of 1295 subjects were included in the study,including 259 subjects in the case group and 1036 subjects in the control group.Univariate analysis showed significant differences between the case and control groups in terms of age,body mass index,history of hypertension,history of alcohol consumption and history of gastroenteritis(all P values<0.05).Multivariate logistic regression analysis identified advanced age[odds ratio(OR)=2.22,95%CI:(1.66,2.97)],overweight[OR=1.75,95%CI:(1.02,2.97)],history of hypertension[OR=1.60,95%CI:(1.19,2.15)],history of alcohol consumption[OR=1.50,95%CI:(1.07,2.08)]and history of gastroenteritis[OR=1.56,95%CI:(1.03,2.36)]as risk factors of gastric cancer.Conclusions Advanced age,overweight,history of hypertension,history of alcohol consumption and history of gastroenteritis are risk factors of gastric cancer.Effective control measures tailored to risk factors are required to reduce the risk of gastric cancer.

关 键 词：胃癌 倾向性评分匹配 LOGISTIC回归分析 影响因素 

分 类 号：R735.2[医药卫生—肿瘤]