药用氯化钇[^(90)Y]溶液中锶[^(90)Sr]分析方法  

Analysis Method of Strontium[^(90)Sr] in Medical Yttrium[^(90)Y]Chloride Solution

作　　者：杨垚 于坤茹 马超 韦贤理 黎玉萍 李星垣 曹小冬 YANG Yao;YU Kunru;MA Chao;WEI Xianli;LI Yuping;LI Xingyuan;CAO Xiaodong(Chengdu New Radiomedicine Technology CO.LTD.,Chengdu 610200,China)

机构地区：[1]成都纽瑞特医疗科技股份有限公司,成都610200

出　　处：《同位素》2024年第5期413-418,共6页Journal of Isotopes

基　　金：四川省科技计划项目:胰腺癌精准治疗用放射性药物的临床转化研究(2024JDHJ0050)。

摘　　要：针对药用氯化钇[^(90)Y]溶液中^(90)Sr含量快速检测的分析需求,本研究提出采用DGA树脂分离氯化钇[^(90)Y]溶液中的^(90)Sr,并使用液体闪烁计数器进行测量的方法。研究DGA树脂的上柱酸度和淋洗体积,并进行方法验证。结果表明,该方法检测结果稳定可靠,线性良好,满足^(90)Sr限度<2×10^(-5)Bq/Bq(^(90)Y)的要求,检测时间<2 h,降低了放行检测时间成本和操作人员的辐射剂量。For the rapid analysis of the amoun of ^(90)Sr in medical yttrium[^(90)Y] chloride solution,^(90)Sr was separated from the yttrium[^(90)Y] chloride solution by DGA resin,and measured by a liquid scintillation counter.The acidity and volume the elution were also studied.The results show that this method provides stable and reliable detection results,good linearity,and fully meets the detection requirements of ^(90)Sr with a limit of <2×10^(-5) Bq/Bq(^(90)Y).The detection time is less than 2 hours,reducing the time of release testing and the radiation dose to operators.

关 键 词：氯化钇[^(90)Y]溶液 锶[^(90)Sr] 液体闪烁计数器 DGA 

分 类 号：TL99[核科学技术—核技术及应用] O657.4[理学—分析化学]