益气养血膏联合促红素治疗肿瘤相关性贫血临床观察  

Efficacy observation of Yiqi Yangxue paste and erythropoietin on tumor-induced anemia

作　　者：曹云[1] 李海燕[1] 陈湘燕 王强[1] 张熔熔[1] 周川玉 CAO Yun;LI Hai-yan;CHEN Xiang-yan(Taizhou Jiangyan Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine,Taizhou 225500,China)

机构地区：[1]南京中医药大学附属泰州市姜堰中医院,泰州225500

出　　处：《山西中医》2024年第10期28-30,共3页Shanxi Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局重点研究室开放课题(编号:202249);江苏省泰州市中医药科技发展项目(编号:TZ202215)。

摘　　要：目的:观察益气养血膏联合促红素治疗肿瘤相关性贫血的临床疗效。方法:选取60例肿瘤相关性贫血患者作为研究对象,随机分为两组各30例。对照组予常规基础治疗、促红素6000 IU皮下注射,每周2次;治疗组在对照组基础上予益气养血膏,两组均治疗8周。观察两组血液学指标变化及临床症状的改善情况。结果:治疗组总有效率93.33%明显高于对照组76.67%(P﹤0.05)。治疗后,治疗组血红蛋白、红细胞计数、红细胞压积、CD4+/CD8+水平较治疗前均明显升高(P﹤0.05),且治疗组血红蛋白水平优于对照组(P﹤0.05);治疗组KPS评分、中医症状评分均较治疗前好转(P﹤0.05),且改善程度优于对照组(P﹤0.05)。结论:益气养血膏对于肿瘤相关性贫血治疗效果较好,能明显提高患者生活质量。Objective:To observe the clinical efficacy of Yiqi Yangxue paste and erythropoietin on tumor-induced anemia.Methods:60 cases of patients with tumor-induced anemia were selected as the researched subjects and randomly divided into two groups,30 cases in each group.The control group was treated by routine basic therapy and with subcutaneous injection of 6000 iu erythropoietin twice a week,while the treatment group was treated plus with Yiqi Yangxue paste on the basis of control group.Both groups were treated for 8 weeks.The changes of haematological indexes and the improvement of clinical symptoms were observed in two groups.Results:The total effective rate of treatment group was 93.33%,which was significantly higher than 76.67%of control group(P﹤0.05).The levels of hemoglobin,red blood cell count,hematocrit and CD4+/CD8+were significantly increased in treatment group after treatment compared with before treatment(P﹤0.05),and the level of hemoglobin of treatment group was higher than that of control group(P﹤0.05).KPS score and TCM symptom score were improved in treatment group compared with before treatment(P﹤0.05),and the improvement of treatment group was better than that of control group(P﹤0.05).Conclusion:The clinical efficacy of Yiqi Yangxue paste and erythropoietin on tumor-induced anemia is better,which can obviously improve the quality of life of patients.

关 键 词：肿瘤相关性贫血 益气养血膏 促红素 中西医结合疗法 

分 类 号：R730.6[医药卫生—肿瘤] R556[医药卫生—临床医学]