保生皮肤粘膜消毒液联合人干扰素α2b阴道泡腾片治疗宫颈HPV感染患者的疗效分析  

Analysis of the Efficacy of Life-preserving Skin Mucosal Disinfectant Combined with Human Interferon α2b Vaginal Effervescent Tablets in the Treatment of Patients with Cervical HPV Infection

作　　者：季伟[1] JI Wei(Department of Obstetrics and Gynecology,Zhangjiagang First People's Hospital,Suzhou 215600,Jiangsu,China)

机构地区：[1]张家港市第一人民医院妇产科,江苏苏州215600

出　　处：《系统医学》2024年第16期132-135,共4页Systems Medicine

摘　　要：目的 探讨保生皮肤粘膜消毒液联合人干扰素α2b阴道泡腾片在宫颈人乳头瘤病毒(human papillomavirus,HPV)感染患者中的疗效。方法 目的选取2022年1月—2023年12月间张家港市第一人民医院接诊的宫颈HPV感染患者88例,根据治疗方法不同将患者分成两组。对照组44例患者采取人干扰素α2b阴道泡腾片治疗,观察组44例采取保生皮肤粘膜消毒液联合人干扰素α2b阴道泡腾片治疗。对比两组的治疗总有效率、转阴时间、不良反应率。结果 观察组总有效率为97.73%(43/44),高于对照组的84.09%(37/44),差异有统计学意义(χ^(2)=4.950,P<0.05);观察组转阴时间短于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 保生皮肤粘膜消毒液联合人干扰素α2b阴道泡腾片在治疗宫颈HPV感染中的效果更为确切,可促进HPV亚型的转阴。Objective To investigate the efficacy of life-preserving skin and mucosa disinfectant combined with human interferon α2b vaginal effervescent tablet in patients with cervical HPV infection.Methods Eighty-eight patients with cervical HPV infection admitted to Zhangjiagang First People's Hospital from January 2022 to December 2023were objectively selected and divided into two groups by different treatment methods.Forty-four patients in the control group were treated with human interferon α2b vaginal effervescent tablets,and forty-four patients in the observation group were treated with life-preserving skin and mucosa disinfectant combined with human interferon α2b vaginal effervescent tablets.The total effective rate,negative conversion rate and adverse reaction rate of the two groups were compared.Results The total effective rate in the observation group was 97.73%(43/44),higher than 84.09%(37/44) in the control group,the difference was statistically significant (χ^(2)=4.950,P<0.05).The time of turning negative in observation group was shorter than that in control group,the difference was statistically significant (P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion Life-preserving skin and mucous membrane disinfectant combined with human interferon α2b vaginal effervescent tablet is more effective in the treatment of cervical HPV infection,and can promote the negative transformation of HPV subtypes.

关 键 词：人乳头瘤病毒感染 保生皮肤粘膜消毒液 人干扰素α2b阴道泡腾片 有效性 

分 类 号：R737[医药卫生—肿瘤]