养阴润目方核桃灸联合玻璃酸钠滴眼液治疗干眼症临床研究  

Clinical Study on Walnut Moxibustion with Yangyin Runmu Prescription Combined with Sodium Hyaluronate Eye Drop for Xerophthalmia

作　　者：冯海童 周佳 俞晓艺[2] FENG Haitong;ZHOU Jia;YU Xiaoyi(The First Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China)

机构地区：[1]广州中医药大学第一临床医学院,广东广州510405 [2]广州中医药大学第一附属医院,广东广州510405

出　　处：《新中医》2024年第19期126-130,共5页New Chinese Medicine

摘　　要：目的:观察养阴润目方核桃灸联合玻璃酸钠滴眼液治疗干眼症临床疗效。方法:选取64例干眼症患者,按随机数字表法分为治疗组及对照组各32例。对照组接受玻璃酸钠滴眼液治疗,治疗组接受养阴润目方核桃灸联合玻璃酸钠滴眼液治疗。比较2组临床疗效,比较2组治疗前后泪液分泌试验(SIT)值、泪河高度(LTMH)、非接触泪膜破裂时间平均值(NIBUTav)、眼表疾病指数(OSDI)评分、角膜荧光染色评分(FL)、睑板腺评分、睑脂性状评分的变化。结果:治疗后,2组SIT、NIBUTav指标值及治疗组LTMH指标值治疗前后比较,差异均有统计学意义(P<0.05);治疗组SIT、LTMH、NIBUTav指标值均高于对照组,差异均有统计学意义(P<0.05)。治疗后,2组OSDI评分、睑脂性状评分及治疗组FL评分治疗前后比较,差异均有统计学意义(P<0.05);治疗组OSDI评分、FL评分均低于对照组,差异均有统计学意义(P<0.05)。治疗组临床疗效总有效率为86.67%,对照组总有效率为56.67%,2组比较,差异有统计学意义(P<0.05)。结论:养阴润目方核桃灸联合玻璃酸钠滴眼液治疗干眼症临床疗效较好,可改善泪液分泌量及泪膜稳定性,缓解临床症状。Objective:To observe the clinical effect of walnut moxibustion with Yangyin Runmu Prescription combined with Sodium Hyaluronate Eye Drop on xerophthalmia.Methods:A total of 64 cases of patients with xerophthalmia were selected and divided into the treatment group and the control group with 32 cases respectively according to random number table method.The control group was treated with Sodium Hyaluronate Eye Drop,and the treatment group was treated with walnut moxibustion with Yangyin Runmu Prescription combined with Sodium Hyaluronate Eye Drop.The clinical effects in the two groups were compared;the changes in Schirmer's Test(SIT),lower tear meniscus height(LTMH)average,noninvasive breakup time(NIBUTav),Ocular Surface Disease Index(OSDI),corneal fluorescin average staining scores(FL),meibomian gland scores and palpebral sebum trait scores before and after treatment were compared between the two groups.Results:After treatment,the values of SIT and NIBUTav in the two groups,as well as the LTMH value in the treatment group,showed significant differences when compared before and after treatment(P<0.05);the values of SIT,LTMH and NIBUTav in the treatment group were higher than those in the control group,differences being significant(P<0.05).After treatment,the OSDI scores,palpebral sebum trait scores in the two groups,and the FL score in the treatment group showed significant differences when compared before and after treatment(P<0.05);OSDI score and FL score in the treatment group were lower than those in the control group,the difference being significant(P<0.05).The total effective rate of clinical effect was 86.67%in the treatment group,and the total effective rate was 56.67%in the control group,the difference between the two groups being significant(P<0.05).Conclusion:Walnut moxibustion with Yangyin Runmu Prescription combined with Sodium Hyaluronate Eye Drop has a good clinical effect in the treatment of xerophthalmia,which can improve tear secretion and film stability and relieve clinical symptoms.

关 键 词：干眼症 养阴润目方 核桃灸 玻璃酸钠滴眼液 泪液分泌量 泪河高度 

分 类 号：R777.34[医药卫生—眼科]