Inflammatory indicators such as systemic immune inflammation index(SIII),systemic inflammatory response index(SIRI),neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)as prognostic factors of curative hepatic resections for hepatocellular carcinoma  

作　　者：Paschalis Gavriilidis Timothy M.Pawlik 

机构地区：[1]Department of Surgery,Colchester General Hospital,Colchester,UK [2]Department of Surgery,The Ohio State University Wexner Medical Center,James Comprehensive Cancer Center,Columbus,OH,USA

出　　处：《Hepatobiliary Surgery and Nutrition》2024年第3期509-511,共3页肝胆外科与营养（英文）

摘　　要：As the fifth most common gastrointestinal cancer worldwide,hepatocellular carcinoma(HCC)often presents at advanced stages of disease.For the subset of patients who present with tumor and liver-related features amenable to surgery,hepatic resection—in addition to transplantation—offers the best chance at curative-intent therapy.Resection can be associated,however,with risk of complications and perioperative death especially among individuals with concomitant portal hypertension,liver fibrosis,cirrhosis,and portal vein thrombosis(1-3).Post-resection liver failure is also a major concern and can be a devasting complication following hepatic resection(4,5).Overall survival following hepatic resection of HCC ranges from only 30–50%,and recurrence can be common depending on the stage of disease.In turn,there is considerable interest in identifying markers to help stratify patients relative to risk of recurrence and prognosis to define which groups of patients may benefit the most from hepatic resection of HCC(1-5).

关 键 词：Hepatocellular carcinoma(HCC) systemic immune inflammation index(SIII) systemic inflammatory index neutrophil-to-lymphocyte ratio(NLR) platelet-to-lymphocyte ratio(PLR) 

分 类 号：R735.7[医药卫生—肿瘤]