Simulating the in vivo tumor microenvironment-advances in building a vascularized model of hepatocellular carcinoma through 3D bioprinting  

作　　者：Liwei Du Huayu Yang 

机构地区：[1]Department of Liver Surgery,Peking Union Medical College(PUMC)Hospital,PUMC&Chinese Academy of Medical Sciences(CAMS),Beijing,China

出　　处：《Hepatobiliary Surgery and Nutrition》2024年第5期882-884,共3页肝胆外科与营养（英文）

基　　金：supported by the National Natural Science Foundation of China(No.32271470).

摘　　要：Over the past decade,there has been notable progress in the systemic treatment of liver cancer.However,despite the emergence of new therapeutic strategies,they have not universally achieved success,with patients afflicted by liver diseases frequently displaying resistance to these treatments(1).Consequently,liver cancer remains a global health challenge,and hepatocellular carcinoma(HCC)stands as the fourth most common cause of cancer-related deaths globally,constituting 80-90%of primary liver cancer cases(2,3).This poses a substantial threat to both the survival and overall well-being of individuals.

关 键 词：Three-dimensional bioprinting(3D bioprinting) hepatocellular carcinoma(HCC) vascularized model individualized treatment Submitted Mar 

分 类 号：R735.7[医药卫生—肿瘤]