Liver Transplantation Reverses Hepatic Myelopathy in the Decompensated Phase of Cirrhosis:Case Report and Literature Review  

作　　者：Jiajun Li Sile Wan Fukai Wen Qingyu Li Yifeng Cui Zhaoyang Lu Han Lin 

机构地区：[1]Department of Hepatic Surgery,The First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,China

出　　处：《Journal of Clinical and Translational Hepatology》2024年第4期436-442,共7页临床与转化肝病杂志（英文版）

基　　金：supported by The National Natural Scientific Foundation of China(Grant No.81972230).

摘　　要：Hepatic myelopathy(HM)is a rare neurological complication in the end stage of many liver diseases and is characterized by bilateral spastic paraparesis without sensory and sphinc-ter dysfunction.It occurs owing to metabolic disorders and central nervous system dysfunction associated with cirrhosis.Without timely and effective clinical intervention,the progno-sis of these patients is devastating.Although liver transplan-tation(LT)is an effective treatment for HM,the prognosis of these patients remains unsatisfactory.Early recognition and diagnosis of this disease are essential for improving patient prognosis.Here,we report a case of hepatitis B virus-asso-ciated decompensated cirrhosis with HM.The patient recov-ered well after LT.We also summarize the clinical character-istics and post-transplant outcomes of 25 patients with HM treated by LT through 2023,including this case.

关 键 词：Hepatic myelopathy Hepatic encephalopathy Spastic paraparesis Portosystemic shunt Liver transplantation 

分 类 号：R575.2[医药卫生—消化系统]