阿尔茨海默病早发现和早诊断与药物研发现状  

The current state of Alzheimer’s disease early detection,diagnosis and drug development

作　　者：周显波 裴中[3] Xianbo ZHOU;Zhong PEI(AstraNeura,Co.,Ltd.,Shanghai 200131,China;Center for Alzheimer's Research,Washington Institute of Clinical Research,Vienna,VA 22181,USA;The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]阿斯诺来(上海)医药科技有限公司,上海200131 [2]美国华盛顿临床研究学院阿尔茨海默研究中心,Vienna,VA 22181 [3]中山大学附属第一医院,广州510080

出　　处：《阿尔茨海默病及相关病杂志》2024年第4期243-246,241,共5页Chinese Journal of Alzheimer's Disease and Related Disorders

摘　　要：阿尔茨海默病是老龄化社会面临的一个重大问题,对全球社会经济造成严重负担。虽然近年来其相关研究有了一系列重大进展,为病人及其家人带来了更多的早发现和诊疗方案,但颠覆性的早发现和诊疗方案尚在研发中。对全球在及时、及早发现,早诊断和药物研发方面最新的有前景的进展做了概述和展望,期待通过及时、及早发现,早诊断和精准神经学可以更好地管理病人,通过靶向神经免疫/多机制以及鸡尾酒疗法早日开发出革命性新药,切实解决这个世界难题。Alzheimer’s disease is a huge societal issue and places a serious economic burden on the ever-aging society.Although tremendous progresses have been made in the early detection,diagnosis and treatment which bring new options and hope for patients and their families,transformative early detection,diagnosis and treatment are still being developed.Here we report the current state of AD early detection,diagnosis and drug development where promising progress are made and hopefully revolutionary therapies will be developed soon to solve this global issues with the help of timely detection,early diagnosis and precision neurology through targeting immunoneurology/multi-mechanisms and cocktail medicine.

关 键 词：阿尔茨海默病 及时发现 早诊断 药物研发 精准神经学 

分 类 号：R74[医药卫生—神经病学与精神病学]