甲状腺相关性眼病活动性和疗效的影像学评估  

Imaging assessment of the activity and treatment efficacy of thyroid associated ophthalmopathy

作　　者：柳宇 李梦婷[1] 陈宏[2] 刘伟[2] 丁颖[1] 张立 邓银倩 陈环宇 赵敏 夏晓天[1] 曹卫[1] Liu Yu;Li Mengting;Chen Hong;Liu Wei;Ding Ying;Zhang Li;Deng Yinqian;Chen Huanyu;Zhao Min;Xia Xiaotian;Cao Wei(Department of Nuclear Medicine,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Key Laboratory of Molecular Imaging,Key Laboratory of Biological Targeted Therapy of the Ministry of Education,Wuhan 430022,China;Department of Ophthalmology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Department of Nuclear Medicine,the Third Xiangya Hospital,Central South University,Changsha 410013,China)

机构地区：[1]华中科技大学同济医学院附属协和医院核医学科、分子影像湖北省重点实验室、生物靶向治疗教育部重点实验室,武汉430022 [2]华中科技大学同济医学院附属协和医院眼科,武汉430022 [3]中南大学湘雅三医院核医学科,长沙410013

出　　处：《中华核医学与分子影像杂志》2024年第10期628-632,共5页Chinese Journal of Nuclear Medicine and Molecular Imaging

基　　金：中国健康促进基金会2020年甲状腺中青年医生研究项目;北京健康促进会2022年甲状腺中青年医生研究项目(BJHPA-2022-JZHXZHQNYJ-LCH-03);分子影像湖北省重点实验室开放基金(2020FZYX016)。

摘　　要：甲状腺相关性眼病(TAO)是一种器官特异性自身免疫性疾病。TAO分为活动期和非活动期,准确判断疾病的活动性是选择恰当治疗方案的关键。临床活动性评分(CAS)是目前评估TAO活动性分期的主要手段,但该方法具有一定主观性。随着影像学技术的发展,超声、CT、MRI以及放射性核素显像逐步应用于TAO的临床诊疗中,并从解剖及功能代谢层面对CAS进行补充,不仅可更好地判断TAO活动性,而且还在疗效评估方面发挥了优势。该文就各种医学影像学检查方法在TAO活动性和疗效评估中的临床价值展开综述。Thyroid associated ophthalmopathy(TAO)is an organ-specific autoimmune disease.TAO is clinically classified into active and inactive stage,and the accurate judgment is the key point of treatment choice.Clinical activity score(CAS)is often used for the assessment of TAO activity,which is subjective to some extent.With the development of imaging techniques,ultrasonography,CT,MRI and radionuclide imaging have gradually been applied into the diagnosis and treatment of TAO.What′s more,the imaging is an important complement to CAS from the aspects of anatomical and functional metabolism,which can better assess the activity and the therapy response of TAO.The clinical value of medical imaging in activity and treatment efficacy evaluation of TAO is reviewed in this article.

关 键 词：GRAVES眼病 超声检查 体层摄影术 X线计算机 磁共振成像 放射性核素显像 发展趋势 

分 类 号：R771.3[医药卫生—眼科] R581[医药卫生—临床医学] R445