Convenient Self-Heating Instant Food Causes Significant Increasing Human Exposure to Organophosphate Esters  

作　　者：Xiaomin Li Yuhan Yin Wei Zhou Hongting Li Boyuan Hu Yajing Cui Ruoxian Zhou Peilong Wang Jianjie Fu 

机构地区：[1]Institute of Quality Standard and Testing Technology for Agro-Products,The Chinese Academy of Agricultural Sciences(CAAS),Beijing 100081,China [2]State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China [3]School of Environment,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China

出　　处：《Environment & Health》2024年第1期52-61,共10页环境与健康（英文）

基　　金：supported by the National Natural Science Foundation of China (22276214,22022611,and 21777190);the Youth Innovation Promotion Association CAS (Y2022020).

摘　　要：The self-heating lunch box(SHLB)is a kind of popular instant food in China,yet little is known about the associated chemical release risk during its heating process.In this study,we investigated organophosphate esters(OPEs)in original unheated food(UF),SHLB-heated processed food(HF)and potential OPE release from SHLB packaging materials.Significantly higher concentrations of OPEs were observed in HF(267±246 ng/g dry weight(dw))than in UF(163±211 ng/g dw)(p<0.001),suggesting an introduction of additional OPEs during heating processes.Tris(2-chloroethyl)phosphate,triethyl phosphate,and tris(2-chloroisopropyl)phosphate exhibited the highest absolute increased amounts,with 137,48.8,and 149%growth in HF than in UF,respectively.Migration testing revealed that packaging materials were rich in OPEs and can release considerable OPEs into food simulates(range,14.7-90.8 ng/g;mean,47.9±21.8).Influencing factors(temperature,contact time,oily food)on OPE migration from packaging materials to food were assessed.Higher temperature and longer contact time increased OPE contents in food simulates.Moreover,the presence of abundant OPEs in UF and significant correlations among different OPEs(p<0.05)suggested contamination happened during food processing and storage.With one SHLB meal a day,a 12-fold increase of OPE intake was observed for humans compared to those following a traditional dietary habit.In the high-exposure(95th percentile)scenario,hazard quotients of nine OPEs ranged from 0.00005 to 0.05.Our results suggested that the SHLB exposure pathway of OPEs should be particularly paid attention to in specific subpopulations that prefer this dietary habit.

关 键 词：Organophosphate esters Self-heating lunch box Migration influencing factors Human exposure 

分 类 号：R15[医药卫生—营养与食品卫生学]