Illuminating thepath to pancreatic cancer  

作　　者：Hiroyuki Kato Nabeel Bardeesy 

机构地区：[1]Krantz Family Center for Cancer Research,Massachusetts General Hospital,Boston,MA,USA [2]Department of Medicine,Harvard Medical School,Boston,MA,USA [3]Broad Institute of MIT and Harvard,Cambridge,MA,USA.

出　　处：《Cell Research》2024年第10期681-682,共2页细胞研究（英文版）

摘　　要：Braxton and colleagues used 3D histological reconstruction and multi-region genomic analysis to understand the microanatomy and model the progression of pancreatic intraepitheliai neoplasias(PaniNs),precursors of pancreatic ductal adenocarcinoma(PDAC).Their study revealed the unexpected prevalence,spatial distribution,and genetic heterogeneity of PaniNs,illuminating their developmental trajectories toward PDAC.

关 键 词：ANATOMY ADENOCARCINOMA HISTOLOGICAL 

分 类 号：R730[医药卫生—肿瘤]