DCE-MRI、DWI对卵巢囊腺肿瘤侵袭性的鉴别诊断效能  

Differential diagnosis efficacy of dynamic contrast enhanced MRI and diffusion weighted imaging for the invasiveness of ovarian cystie adenoma

作　　者：沈燕琴 李志 SHEN Yanqin;LI Zhi(Huzhou Maternal and Child Health Care Hospital,Huzhou,Zhejiang Province,313000)

机构地区：[1]浙江省湖州市妇幼保健院,313000

出　　处：《中国计划生育学杂志》2024年第10期2406-2410,共5页Chinese Journal of Family Planning

摘　　要：目的:分析动态对比增强成像(DCE-MRI)、弥散加权成像(DWI)对卵巢囊腺肿瘤侵袭性的鉴别诊断效能。方法:选取2021年9月-2023年12月本院就诊的卵巢囊腺肿瘤患者104例进行回顾性分析。依据病理诊断分为卵巢囊腺癌(OCAC)组、卵巢囊腺瘤(OCA)组。收集MRI资料[测量容量转移常数(Ktrans)、表观扩散系数(ADC)、噪声比(CNR)等],对照病理结果进行统计分析,受试者工作特征(ROC)曲线分析相关参数对卵巢囊腺肿瘤侵袭性的鉴别诊断价值。结果:104例卵巢囊腺肿瘤患者,病理诊断OCAC 14例、OCA 90例。OCAC组Ktrans值高于OCA组,CNR、ADC值低于OCA组(P<0.05)。ROC分析发现,Ktrans(AUC=0.973,95%CI 0.920~0.995,P<0.001)、CNR(AUC=0.854,95%CI 0.772~0.916,P<0.001)、ADC(AUC=0.793,95%CI 0.703~0.866,P<0.001)参数单独及联合检测(AUC=0.994,95%CI 0.955~1.000,P<0.001)对鉴别诊断OCAC均具有一定价值,联合检测鉴别诊断效能最高。结论:DCE-MRI与DWI在卵巢囊腺肿瘤侵袭性鉴别诊断中具有肯定价值,且Ktrans、CNR、ADC参数联合检测鉴别诊断效能最高。Objective:To analyze the differential diagnosis efficacy of dynamic contrast enhanced MRI(DCE-MRI)and diffusion weighted imaging(DWI)for the invasiveness of ovarian cystic adenoma.Methods:A retrospective analysis was performed on 104 patients with ovarian cystadenoma in hospital from September 2021 to December 2023.According to the pathological diagnosis,these patients were divided into group A(patients with ovarian cystadenocarcinoma(OCAC))and group B(patients with ovarian cystadenoma(OCA)).The women in the two groups were given DCE-MRI and DWI examinations.The MRI data,such as measuring volume transfer constant(K~(trans)),apparent diffusion coefficient(ADC),noise ratio(CNR),and so on,of the patients were collected and were statistically analyzed based on their pathological results.Receiver operating characteristic(ROC)curve was used to analyze the differential diagnostic value of the related parameters of DCE-MRI and DWI examinations of the patients for their invasiveness of OCAC.Results:The K~(trans)value of the patients in group A was significantly higher than that of the patients in group B,and the CNR and ADC values of the patients in group A were significantly lower than those of the patients in group B(P<0.05).ROC analysis showed that the K~(trans)value(AUC=0.973,95%CI 0.920-0.995,P<0.001),the CNR value(AUC=0.854,95%CI 0.772-0.916,P<0.001),the ADC value(AUC=0.793,95%CI 0.703-0.866,P<0.001),and the value of the combined detections of K~(trans),CNR and ADC(AUC=0.994,95%CI 0.955-1.000,P<0.001)of the patients for differential diagnosing their invasiveness of OCAC had certain values,and the value of the combined detections of Ktrans,CNR and ADC had the highest differential diagnosis efficiency.Conclusion:DCE-MRI and DWI of the patients for differential diagnosing their invasiveness of OCAC have the identified value,and the value of the combined detections of Ktrans,CNR and ADC has the highest differential diagnosis efficiency.

关 键 词：卵巢囊腺癌 卵巢囊腺瘤 核磁共振成像 动态对比增强成像 弥散加权成像 容量转移常数 噪声比 表观扩散系数 鉴别诊断 

分 类 号：R737.31[医药卫生—肿瘤] R445.2[医药卫生—临床医学]