低温等离子射频消融术治疗早期声门型喉癌患者的有效性分析  

Effectiveness analysis of low temperature plasma radiofrequency ablation in the treatmentof earlyglotticlaryngeal carcinoma

作　　者：石庆敏 胡树影 王静 Shi Qingmin;Hu Shuying;Wang Jing(Dezhou Second People's Hospital,Dezhou,Shandong,253000,China)

机构地区：[1]德州市第二人民医院,山东德州253000

出　　处：《中国医学文摘（耳鼻咽喉科学）》2024年第5期24-27,共4页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的评估低温等离子射频消融术(RFA)应用在早期声门型喉癌(EGC)患者中的有效性。方法纳入2017年1月-2021年12月的50例EGC患者,参照随机数字表法划分对照组(纳入25例,行垂直半喉切除术)、观察组(纳入25例,行RFA),评价组间疾病控制率(DCR)、治疗相关参数、噪音功能、术后并发症。结果(1)较之对照组,观察组DCR更高,治疗相关参数更佳,术后并发症更少,P<0.05;(2)术前,组间振幅微扰、谐噪比、基频无差异,P>0.05;术后1个月,观察组振幅微扰、基频更低,谐噪比更高,P<0.05。结论对EGC患者行RFA,可以提高疗效,减少并发症,改善嗓音功能及手术相关指标,值得推广。Objective To evaluate the efficacy of low temperature plasma radiofrequency ablation(RFA)in patients with early glottic laryngeal carcinoma(EGC).Methods Fifty patients with EGC from January 2017 to December 2021 were included and divided into control group(25 patients included,receiving vertical hemilaryngectomy)and observation group(25 patients included,receiving RFA)according to random number table method.Inter-group disease control rate(DCR),treatment-related parameters,voice function,and postoperative complications were evaluated.Results(l)Compared with the control group,the observation group had higher DCR,better parameters related to treatment,and fewer postoperative complications,P<0.05;(2)Before surgery,there were no differences in amplitude perturbation,harmonic to noise ratio and fundamental frequency between groups(P>0.05).One month after operation,the amplitude perturbation and fundamental frequency were lower and the harmonic to noise ratio was higher in the observation group(P<0.05).Conclusion RFA in patients with EGC can improve efficacy,reduce complications,improve voice function and related indexes of surgery,which is worth promoting.

关 键 词：低温等离子射频消融术 早期声门型喉癌 嗓音功能 

分 类 号：R73[医药卫生—肿瘤]