Limited recovery following acellular nerve allograft reconstruction in major peripheral nerve injuries  

作　　者：David Chi Anna Rose Johnson Susan E.Mackinnon 

机构地区：[1]Division of Plastic and Reconstructive Surgery,Department of Surgery,Washington University School of Medicine,Saint Louis,MO 63110,USA

出　　处：《Plastic and Aesthetic Research》2023年第1期676-679,共4页整形与美容研究（英文版）

摘　　要：Recent studies suggest that acellular nerve allografts(ANA)have similar efficacy as nerve autografts in certain applications of nerve surgery.However,multiple studies also demonstrate the limitations of nerve allografts,resulting in poor patient outcomes.This submission discusses a recent case series of patients who failed allograft use with subsequent histologic analyses of these allografts.Recommendations on the treatment of nerve gaps are presented,drawing from our current understanding of allograft and autograft utility in reconstruction.Factors taken into account include recipient critical nerve function,existent nerve gap,and nerve diameter.

关 键 词：Nerve reconstruction peripheral nerve acellular nerve allograft nerve autograft 

分 类 号：R73[医药卫生—肿瘤]