Synthesis, antibacterial evaluation, and safety assessment of Se@PLA as a potent bactericide against Xanthomonas oryzae pv. oryzae  

作　　者：Xingyu Chen Sihui Zhuang Weiyao Yan Zhengli Zeng Jianguo Feng Hongen Cao Lei Yu 

机构地区：[1]College of Plant Protection,Yangzhou University,Yangzhou 225009,China [2]School of Chemistry and Chemical Engineering,Yangzhou University,Yangzhou 225002,China

出　　处：《Chinese Chemical Letters》2024年第10期253-256,共4页中国化学快报（英文版）

基　　金：National Key Research and Development Program of China(No.2018YFD0200100);the fund of the joint-laboratory of Shanghai Dingya Pharmaceutical Chemical Technology Co.,Ltd.with Yangzhou University(2022–2027);the Yangzhou City and Yangzhou University Cooperation Program(No.YZ2023209);the Priority Academic Program Development of Jiangsu Higher Education Institutions for support。

摘　　要：A novel biodegradable material,Se@PLA,was designed and prepared via the selenization reaction of polylactic acid using NaHSe as the selenization reagent.This material shows excellent antibacterial activity(EC_(5)0=13.38μg/mL)against Xanthomonas oryzae pv.Oryzae,which is a highly destructive pathogen responsible for rice bacterial blight.Se@PLA induces oxidative stress in bacteria,leading to the rupture of bacterial cell membranes and eventual death.Moreover,Se@PLA can significantly inhibit the motility of bacteria and is low toxic to soil and aquatic organisms.This work provides an effective method for preventing and controlling rice bacterial blight,and reveals the great potential of using Se@PLA as an alternative next generation plant bactericide.

关 键 词：Selenium Antibacterial activity OXIDATIVESTRESS Bacterium motility ENVIRONMENT-FRIENDLY 

分 类 号：TQ455[化学工程—农药化工]