Improving Long-Term Functional Outcomes of Ischemic Stroke in the Reperfusion Era  

作　　者：Chuanjie Wu Xuehong Chu Zhanwei Zhu Di Wu Xunming Ji 

机构地区：[1]Department of Neurology,Xuanwu Hospital Capital Medical University,Beijing 100053,China [2]China-America Institute of Neuroscience,Xuanwu Hospital Capital Medical University,Beijing 100053,China

出　　处：《Engineering》2024年第9期15-18,共4页工程（英文）

基　　金：supported by the National Natural Science Foundation of China(82027802,82371470,and 82071468).

摘　　要：1.Introduction Stroke remains the second leading cause of death and the third leading cause of death and disability combined worldwide,as indicated by disability-adjusted life-years(DALYs)lost[1].The highest burden of stroke disability is observed in developing countries of Asia and the stroke belt of the United States[2].Despite remarkable progress and advancements in evidence-based acute care therapies,such as intravenous thrombolysis and endovascular therapy,the burden of stroke remains significantly high[3].In 2023,a significant advancement in the treatment of ischemic stroke due to proximal intracranial arterial occlusion was marked by compelling evidence from several clinical trials that supported endovascular therapy,particularly for patients with a large ischemic core[4].Thus,endovascular therapy has entered a new era since the first clinical trial favoring endovascular therapy.However,more patients receiving endovascular therapy does not equal a better prognosis.Patients with stroke experience long-term dysfunction,and the percentage is much higher in patients with large ischemic cores.Therefore,numerous tasks must be performed to optimize acute stroke treatment strategies and improve rehabilitative care.

关 键 词：ACUTE treatment SPITE 

分 类 号：R743.3[医药卫生—神经病学与精神病学]