A case of central nervous system infection with Scedosporium boydii  

作　　者：Zhen Cai Dongchao Pan Ronghua Geng Jidi Fu Fen Qu 

机构地区：[1]Department of Clinical Laboratory,Aviation General Hospital,Beijing,China [2]Chinese Academy of Medical Sciences&Peking Union Medical College,Plastic Surgery Hospital and Institute,Beijing,China

出　　处：《iLABMED》2024年第3期221-225,共5页智能检验医学（英文）

摘　　要：Scedosporium boydii is considered an opportunist fungal pathogen in immunocompromised patients.It also causes serious and fatal central nervous system infections.In this study,a man with brain abscesses infected with S.boydii was diagnosed using multiple methods,including microscopy,culture combined with Matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MOLDI-TOF MS),internal transcribed spacer sequencing and Metagenomic next-generation sequencing(mNGS).This successful diagnosis highlights the importance of using a variety of techniques to identify and treat infections caused by this dangerous fungus.

关 键 词：central nervous system MOLDI-TOF MS mNGS Scedosporium boydii 

分 类 号：R745[医药卫生—神经病学与精神病学]