Decoding the brain:Unveiling comprehensive cellular atlases through multiomics mega-data  

作　　者：Qianwen Wang Wenli Tang Lukui Chen Lin Deng Guangchuang Yu 

机构地区：[1]Department of Bioinformatics,School of Basic Medical Sciences,Southern Medical University,Guangzhou 510515,China [2]Department of Neurosurgery,Southern Medical University Hosptial of Integrated Traditional Chinese and Western Medicine,Southern Medical University,Guangzhou 510515,China

出　　处：《The Innovation》2024年第4期9-10,共2页创新（英文）

基　　金：supported by grants from the National Natural Science Foundation of China(32270677);Guangzhou Municipal Science and Technology Bureau(2024A04J5003).

摘　　要：The pursuit to comprehend the intricate nature of the brain,an organ of unparalleled complexity,remains a persistent endeavor in the field of neuroscience.1 Recent strides by the National Institutes of Health’s BRAIN Initiative–Cell Census Network(BICCN)have yielded comprehensive cellular atlases for mice and humans,2,3 published in Nature and Science,respectively.Additionally,a 3D cell-type atlas of the macaque brain,contributed by Cell,offers profound insights into non-human primate cortical intricacies.4 These collaborative initiatives,driven by the US’s BICCN and China’s Brain Project,represent a significant leap forward in unraveling the cellular intricacies of the brain,culminating in groundbreaking exploration across mice,non-human primates,and humans.The confluence of these works serves to elucidate the intricate cellular landscapes of the brain through a multiomics approach,signifying a pivotal advancement in neuroscience research toward comprehensive understanding and collaborative exploration(Figure 1).

关 键 词：COMPREHENSIVE FIGURE landscape 

分 类 号：R741[医药卫生—神经病学与精神病学]