炎性肠病合并非酒精性脂肪性肝病相关危险因素研究进展  

Research Progress of Risk Factors Related to Inflammatory Bowel Disease Combined with Nonalcoholic Fatty Liver Disease

作　　者：常宗宏 周馨瑜 秦晨玮 孙霞 杨永林 CHANG Zonghong;ZHOU Xinyu;QIN Chenwei;SUN Xia;YANG Yonglin(Endoscopy Center,Gansu Provincial Cancer Hospital,Lanzhou 730050,China)

机构地区：[1]甘肃省肿瘤医院内镜中心,兰州730050

出　　处：《医学综述》2024年第22期2746-2750,共5页Medical Recapitulate

摘　　要：非酒精性脂肪性肝病(NAFLD)是炎性肠病(IBD)常见的肝脏合并症之一,这可能与肠道通透性改变、肠道失调和慢性炎症等因素相关,但具体的发病机制以及相互作用机制尚不明确。近年来,IBD患者的NAFLD发病率逐年升高,而相关危险因素(患者特征、疾病因素、代谢因素和治疗方式)对IBD合并NAFLD防治至关重要。未来,应深入研究IBD合并NAFLD的病因和发病机制,以实施早期干预措施,降低发病率。Nonalcoholic fatty liver disease(NAFLD)is one of the common liver complications of inflammatory bowel disease(IBD),which may be related to factors such as changes in intestinal permeability,intestinal dysregulation,and chronic inflammation.However,the specific pathogenesis and interaction mechanisms are not yet clear.In recent years,the incidence of NAFLD in IBD patients has been increasing year by year,and the disease related risk factors(patient features,disease factors,metabolic factors and treatment methods)are crucial for the prevention and treatment of IBD combined with NAFLD.In the future,the etiology and pathogenesis of IBD combined with NAFLD should be further studied,so as to implement early intervention measures and reduce the incidence.

关 键 词：炎性肠病 非酒精性脂肪性肝病 危险因素 

分 类 号：R574[医药卫生—消化系统] R575.5[医药卫生—内科学]