中国多病共存老年人夜间睡眠时长对抑郁症状的影响分析  

Correlation analysis between nighttime sleep and depression in elderly people with multiple coexisting diseases in China

作　　者：安景荣·安治国 那仁 徐斌[1] Anjingrong·Anzhiguo;NA Ren;XU Bin(Psychological Medicine Center of the First Affiliated Hospital of Xinjiang Medical University,Xinjiang Clinical Medical Research Center for Mental(Psychological)Disorders,Urumqi,Xinjiang 830054,China;不详)

机构地区：[1]新疆医科大学第一附属医院心理医学中心新疆精神(心理)疾病临床医学研究中心,新疆乌鲁木齐830054 [2]新疆广播电视大学

出　　处：《现代预防医学》2024年第20期3748-3755,共8页Modern Preventive Medicine

基　　金：国家自然科学基金(8196050227);新疆维吾尔自治区自然科学基金(2022D01D64、2024D01C178)。

摘　　要：目的分析我国多病共存老年人生活习惯中夜间睡眠时长对抑郁症状的影响。方法采用第五轮中国健康与养老追踪调查项目,基于流调中心抑郁评定量表(CSE-D-10)对多病共存老年人抑郁情绪进行评估,夜间睡眠划分五级:<6 h、6~<7 h、7~<8 h、8~<9 h、≥9 h,多因素logistic回归分析多病共存老年人发生抑郁的影响因素,随机森林模型分析夜间睡眠在多病共存老年人发生抑郁风险中的重要程度,限制性立方样条曲线进一步探索夜间睡眠时长与发生抑郁风险之间的剂量-反应关系。结果共纳入1249名多病共存老年人,年龄(68.51±5.91)岁,多因素logistic回归分析发现,夜间睡眠6~<7h(OR=0.447(95%CI:0.309~0.646))、7~<8h(OR=0.550(95%CI:0.351~0.862))、8~<9h(OR=0.498(95%CI:0.323~0.768))相对<6 h多病共存老年人发生抑郁的风险降低;因疼痛而难受、ADL、生活满意度、中风是多病共存老年人发生抑郁的影响因素(P<0.05)。随机森林模型结果显示夜间睡眠对抑郁症状影响的重要性评分较高;限制性立方样条曲线结果表明,夜间睡眠与抑郁症状风险之间存在非线性关系,夜间睡眠6~8 h,抑郁症状发生风险下降,夜间睡眠<6 h或>8 h时,抑郁症状发生风险上升。结论夜间睡眠对多病共存老年人抑郁的发生有影响,建议老年人夜间睡眠保持6~8 h,有效降低老年人发生抑郁的风险,对老年人群抑郁症的早期防控具有一定的意义。Objective To analyze the impact of nighttime sleep duration on depressive symptoms in the lifestyle habits of elderly people with multiple comorbidities in China.Methods Using the fifth round of the China Health and Retirement Longitudinal Study project,the depression mood of elderly people with multiple comorbidities was evaluated based on the Center for Disease Control Depression Rating Scale(CSE-D-10).Nighttime sleep was divided into five levels:<6 h,6 to<7 h,7 to<8 h,8 to<9 h,and≥9 h.Multivariate logistic regression analysis was conducted to investigate the influencing factors of depression in elderly people with multiple comorbidities.Random forest model was used to analyze the importance of nighttime sleep in the risk of depression in elderly people with multiple comorbidities.Restrictive cubic spline curves were used to further explore the dose-response relationship between nighttime sleep duration and the risk of depression.Results A total of 1249 elderly individuals with multiple comorbidities were included,aged(68.51±5.91)years.Multivariate logistic regression analysis showed that the risk of depression in elderly individuals with multiple comorbidities who slept at night for 6 to<7 hours(OR=0.447(95%CI:0.309-0.646)),7 to<8 hours(OR=0.550(95%CI:0.351-0.862)),and 8 to<9 hours(OR=0.498(95%CI:0.323-0.768))was relatively lower compared to those who slept for less than 6 hours.Discomfort caused by pain,ADL,life satisfaction,and stroke are the influencing factors for depression in elderly people with multiple comorbidities(P<0.05).The results of the random forest model show that the importance score of nighttime sleep on depression symptoms is relatively high.The results of the restricted cubic spline curve indicate a non-linear relationship between nighttime sleep and the risk of depression symptoms.The risk of depression symptoms decreases with 6-8 hours of nighttime sleep,and increases with less than 6 hours or more than 8 hours of nighttime sleep.Conclusion Nighttime sleep has an impact on the occurren

关 键 词：多病共存 老年人 夜间睡眠 抑郁 

分 类 号：R749.4[医药卫生—神经病学与精神病学]