乏血供和非乏血供脊柱肿瘤动态核磁共振灌注的特征  

Characteristics of dynamic magnetic resonance imaging perfusion in deficient and non-deficient spinal tumors

作　　者：杨俊涛 何全杰 焦勇强 郭光辉[2] 陈俊丽[2] 王玉洁 YANG Jun-tao;HE Quan-jie;JIAO Yong-qiang;GUO Guang-hui;CHEN Jun-li;WANG Yu-jie(Dept of Orthopaedics,Handan Steel Hospital of Handan City,Handan,Hebei 056001,China;Dept of Orthopaedics,the Affiliated Hospital of Hebei University of Engineering,Handan,Hebei 056008,China)

机构地区：[1]邯郸邯钢医院骨科,河北邯郸056001 [2]河北工程大学附属医院骨科,河北邯郸056008

出　　处：《临床骨科杂志》2024年第5期658-661,共4页Journal of Clinical Orthopaedics

基　　金：河北省卫健委技术成果推广项目(编号:20241620)。

摘　　要：目的探讨动态对比增强磁共振(DCE-MRI)在评估脊柱肿瘤血供方面的应用。方法将36例脊柱转移瘤患者先后进行DCE-MRI灌注成像和数字减影血管造影(DSA)检查,根据DSA检查结果将患者分为乏血供组(A组,10例)和非乏血供组(B组,26例)。比较两组DCE-MRI灌注图像上血流量(BF)比值、峰值增强参数、血管通透性(Ktrans)、血浆体积(VP)的差异。结果DCE-MRI灌注图像上VP、BF比值、Ktrans、峰值增强参数B组均大于A组(P<0.05)。结论DCE-MRI评估脊柱肿瘤血供稳定可靠,乏血供脊柱肿瘤和非乏血供脊柱肿瘤的动态核磁共振灌注有明显的差别。Objective To investigate the application of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)perfusion in evaluating the blood supply of spinal tumors.Methods DCE-MRI and digital subtraction angiography(DSA)examination were performed in 36 patients with spinal metastases before and after time.According to the results of DSA examination,the patients were divided into deficient blood supply group(group A,10 cases)and non-deficient blood supply group(group B,26 cases).The blood flow(BF)ratio,peak enhancement parameters,vascular permeability(Ktrans)and plasma volume(VP)on DCE-MRI perfusion images were compared between the two groups.Results On DCE-MRI perfusion images,VP,BF ratio,Ktrans and peak enhancement parameters in group B were higher than those in group A(P<0.05).Conclusions The blood supply of spinal tumors is stable and reliable in DCE-MRI assessment.There is a significant difference in the DCE-MRI perfusion between deficient and non-deficient spinal tumors.

关 键 词：动态增强核磁灌注 血浆体积 脊柱肿瘤 血管通透性 

分 类 号：R738.1[医药卫生—肿瘤] R445.2[医药卫生—临床医学] R816.8