3,3-二苯基-3H-萘并吡喃化合物的合成与光致变色性质——一个综合有机化学实验设计与教学实践  

Synthesis and Photochromic Properties of 3,3-Diphenyl-3HNaphthopyran:Design and Teaching Practice of a Comprehensive Organic Experiment

作　　者：赵以豪 饶继田 韩杰[1] Yihao Zhao;Jitian Rao;Jie Han(National Demonstration Center for Experimental Chemistry Education,College of Chemistry,Nankai University,Tianjin 300071,China)

机构地区：[1]南开大学化学学院,化学国家级实验教学示范中心,天津300071

出　　处：《大学化学》2024年第10期149-155,共7页University Chemistry

基　　金：2022年基础学科拔尖学生培养计划2.0研究项目(20221008);天津市大学生创新项目(202310055362)。

摘　　要：将Claisen重排、光化学反应及固相合成等引入有机化学实验,开发了一个综合有机化学试验——3,3-二苯基-3H-萘并吡喃(3H-NP)的合成与光致变色性质研究。采用液相及固相合成两种方法合成了产物,对比考查了合成方法对收率的影响,并通过紫外-可见吸收光谱研究了产物的光致变色性质的影响。本实验将科学研究过程融入教学实践,有利于培养本科生的科学素质和创新能力。A comprehensive organic experiment,focusing on the synthesis and photochromic properties of 3,3-diphenyl-3H-benzo[f]chromene(3H-NP),was developed by incorporating Claisen rearrangement,photochemical reactions,and solid-phase synthesis.The product was synthesized using both liquid-phase and solid-phase methods,and the impact of different synthetic approaches on yield was compared.The photochromic properties of the product were investigated using UV-Vis absorption spectroscopy.By integrating the scientific research process into teaching practice,this experiment aims to foster scientific literacy and innovation skills among undergraduate students.

关 键 词：3 3-二苯基-3H-萘并吡喃 固相合成 光致变色 CLAISEN重排 绿色化学 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]