膀胱经中药竹罐疗法治疗中虚气逆型胃食管反流病疗效观察  

Observation on the therapeutic effect of the bladder meridian bamboo pot therapy of traditional Chinese medicine for gastro-esophageal reflux disease with Qi deficiency

作　　者：潘红霞[1] 陈洁 刘礼剑[1] 韦金秀 黄晓燕[1] 林奉佼 曹云云[1] PAN Hongxia;CHEN Jie;LIU Lijian;WEI Jinxiu;HUANG Xiaoyan;LIN Fengjiao;CAO Yunyun(Department of Gastroenterology,the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学第一附属医院脾胃病科,广西南宁530023

出　　处：《右江医学》2024年第9期784-789,共6页Chinese Youjiang Medical Journal

基　　金：广西壮族自治区中医药管理局自筹经费科研课题(GZZC2019059)。

摘　　要：目的观察膀胱经中药竹罐疗法治疗中虚气逆型胃食管反流病(GERD)的临床疗效。方法将100例中虚气逆型GERD患者按随机数字表分为中药竹罐组与对照组,每组50例,剔除脱落病例后中药竹罐组42例,对照组46例。中药竹罐组予膀胱经中药竹罐疗法治疗,对照组予枸橼酸莫沙必利片联合雷贝拉唑钠肠溶片治疗,两组疗程均为4周。观察并比较两组患者临床疗效、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、生活质量(SF-36)、匹茨堡睡眠质量量表(PSQI)评分、24 h食管pH检测酸反流情况及复发率。结果(1)治疗结束后,中药竹罐组的总体疗效优于对照组,且愈显率也高于对照组(P<0.05);中药竹罐组及对照组的酸反流时间、反流次数、酸反流时间百分比及DeMeester计分均低于同组治疗前(P<0.01);中药竹罐组的复发率低于对照组(P<0.01)。(2)治疗第4周末,中药竹罐组的HAMA、HAMD及PSQI评分低于治疗前,SF-36评分高于治疗前,且中药竹罐组优于对照组(P<0.01或0.05);随访3个月,中药竹罐组的HAMA、HAMD及PSQI评分低于治疗前(P<0.01),SF-36评分高于治疗前,且中药竹罐组优于对照组(P<0.01);对照组的HAMA及HAMD评分与同组治疗前比较改变不明显(P>0.05)。结论膀胱经中药竹罐疗法治疗GERD患者疗效较好,可显著提高愈显率,改善焦虑抑郁状态,提高睡眠及生活质量,但相关机制有待进一步研究验证。Objective To observe the clinical efficacy of the bladder meridian bamboo pot therapy of traditional Chinese medicine(TCM)for gastro-esophageal reflux disease(GERD)with Qi deficiency.Methods 100 GERD patients with Qi deficiency were randomly divided into TCM bamboo pot therapy group and control group,with 50 cases in each group.After excluding shedding cases,there were 42 cases in the TCM bamboo pot therapy group and 46 cases in the control group.The TCM bamboo pot therapy group were treated with the bladder meridian bamboo pot therapy of TCM,while the control group were treated with citrate mosapride tablets combined with rabeprazole sodium enteric coated tablets.Both groups received a treatment course of 4 weeks.And then,clinical efficacy,Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Rating Scale(HAMA),Quality of Life(SF-36),Pittsburgh Sleep Quality Scale(PSQI)scores,24-hour esophageal pH test acid reflux,and recurrence rate between two groups of patients were observed and compared.Results(1)After treatment,the overall efficacy of the TCM bamboo pot group was better than that of the control group,and the markedly effective rate was also higher than that of the control group(P<0.05);acid reflux time,reflux frequency,the percentage of acid reflux time,and DeMeester score of the TCM bamboo pot group and the control group were all lower than those before treatment in the same group(P<0.01);the recurrence rate of the TCM bamboo pot group was lower than that in the control group(P<0.01).(2)At the end of the fourth week of treatment,the HAMA,HAMD and PSQI scores of the bamboo pot group were lower than those before treatment,the SF-36 score was higher than that before treatment,and the bamboo pot group was better than the control group(P<0.01 or 0.05);during a 3-month follow-up,the HAMA,HAMD and PSQI scores of the TCM bamboo pot group were lower than those before treatment(P<0.01),the SF-36 scores were higher than those before treatment,and the bamboo pot group was better than the control group(P<0.01);HAMA a

关 键 词：膀胱经 中药竹罐疗法 胃食管反流病 

分 类 号：R571[医药卫生—消化系统]