急性脑梗死患者大脑中动脉粥样硬化斑块特征的CT血管造影分析  

CT Angiographic Analysis of Atherosclerotic Plaque Characteristics in the Middle Cerebral Artery of Patients with Acute Cerebral Infarction

作　　者：陈思远 陈晓鹏 彭勃 庄原苏 曹韦 李学忠 宋西珠 Chen Siyuan;Chen Xiaopeng;Peng Bo;Zhuang Yuansu;Cao Wei;Li Xuezhong;Song Xizhu(Department of Neurology,the First People's Hospital of Zhenjiang City,Zhenjiang,Jiangsu 212000;Department of Endocrine,the First People's Hospital of Zhenjiang City,Zhenjiang,Jiangsu 212000)

机构地区：[1]镇江市第一人民医院神经内科,江苏镇江212000 [2]镇江市第一人民医院内分泌科,江苏镇江212000

出　　处：《现代医用影像学》2024年第7期1193-1196,共4页Modern Medical Imageology

基　　金：第二期“金山医者”医学领域人才培养计划(2022-JSYZ-18)。

摘　　要：目的:探讨CT血管造影检查急性脑梗死患者大脑中动脉粥样硬化斑块的特征及其临床意义。方法:选择2022年1月至2023年12月期间的急性脑梗死患者47例为观察组,另外选择同时期CT血管造影技术检测的存在大脑中动脉粥样硬化斑块的非急性脑梗死患者31例为对照组。对比两组大脑中动脉狭窄情况及动脉粥样硬化斑块类型特征,并根据急性脑梗死患者神经功能缺损程度的差异性分析上述指标。结果:观察组与对照组患者间大脑中动脉斑块各项分型占比存在统计学差异,且观察组大脑中动脉狭窄程度较对照组高(P<0.05)。急性脑梗死患者NIHSS评分≥15分时大脑中动脉狭窄程度较NIHSS评分<15分的患者无明显差异(P>0.05),但NIHSS评分≥15分的患者钙化斑块占比明显高于NIHSS评分<15分的患者(P<0.05)。结论:急性脑梗死患者采取CT血管造影技术检测显示大脑中动脉斑块性质主要表现为钙化斑块及混合斑块,动脉狭窄多集中于中度及重度,同时与患者自身神经功能缺损情况具有相关性。Objective:To investigate the characteristics and clinical significance of atherosclerotic plaques in the middle cerebral arteries of acute cerebral infarction patients evaluated by CT angiography.Methods:A total of 47 patients with acute cerebral infarction from January 2022 to December 2023 were selected as the observation group.Additionally,31 patients with atherosclerotic plaques in the middle cerebral arteries detected by CT angiography during the same period but without acute cerebral infarction were selected as the control group.The stenosis of the middle cerebral artery and the characteristics of atherosclerotic plaque types were compared between the two groups.Furthermore,these indicators were analyzed based on the differences in the degree of neurological deficit in patients with acute cerebral infarction.Results:Statistically significant differences were observed in the proportion of various plaque subtypes in the middle cerebral artery between the observation and control groups.Additionally,the degree of stenosis in the middle cerebral artery was higher in the observation group compared to the control group(P<0.05).In patients with acute cerebral infarction,there was no significant difference in the degree of stenosis in the middle cerebral artery between patients with NIHSS scores≥15 and those with NIHSS scores<15(P>0.05).However,the proportion of calcified plaques was significantly higher in patients with NIHSS scores≥15 compared to those with NIHSS scores<15(P<0.05).Conclusion:CT angiography in patients with acute cerebral infarction revealed that the nature of plaques in the middle cerebral artery is mainly characterized by calcified and mixed plaques.Arterial stenosis is mostly concentrated in moderate to severe degrees and is correlated with the patient's neurological deficit status.

关 键 词：CT血管造影 急性脑梗死 动脉粥样硬化斑块 特征 临床意义 

分 类 号：R743.33[医药卫生—神经病学与精神病学]