保留生殖功能的全去带乙状结肠原位膀胱术1例报告并文献复习  

Orthotopic detaenial sigmoid neobladder reconstruction and preservation of reproductive function:a case report and literature review

作　　者：常博 侯一凡 张曼青 张建华 李松 王晨阳 张强强 侯俊清 CHANG Bo;HOU Yifan;ZHANG Manqing;ZHANG Jianhua;LI Song;WANG Chenyang;ZHANG Qiangqiang;HOU Junqing(Department of Urology,Huaihe Hospital of Henan University,Kaifeng 475000,CHN;Medical College of Henan University,Kaifeng 475000,CHN;Department of General Medicine,the First Affiliated Hospital of Henan University,Kaifeng 475000,CHN;Department of Urology,Kaifeng 155 Hospital of China Rongtong Asset Management Group Corporation,Kaifeng 475000,CHN)

机构地区：[1]河南大学淮河医院泌尿外科,河南开封475000 [2]河南大学医学院,河南开封475000 [3]河南大学第一附属医院全科医学科,河南开封475000 [4]中国融通集团开封一五五医院泌尿外科,河南开封475000

出　　处：《河南大学学报（医学版）》2024年第5期365-371,共7页Journal of Henan University:Medical Science

基　　金：河南省科技攻关计划(232102310416);河南省医学科技攻关计划项目(LHGJ20230435,LHGJ20230425);河南省高等学校重点科研项目计划(23A320039)。

摘　　要：目的:探讨保留生殖功能的全去带乙状结肠原位新膀胱术的初步经验。方法:对收治的1例接受保留生殖功能的全去带乙状结肠原位新膀胱术患者的诊疗经过进行回顾性分析,结合相关文献复习归纳,总结临床经验。结果:该患者接受经尿道前列腺等离子剜除术+腹腔镜膀胱癌根治性切除术+全去带乙状结肠原位新膀胱术,术中保留前列腺外科包膜及双侧精囊,术后随访10个月,未出现肿瘤转移,同时结合术后相关检查,患者的尿控及性功能恢复令人满意。结论:经过严格的术前筛选,对有意愿保留生殖功能的男性膀胱癌患者,行此术式能极大的提高生活质量,但未来需要大样本的随机对照研究及长时间随访进一步验证。Objective:To investigate the preliminary outcomes of orthotopic sigmoid neobladder reconstruction with total decortication,while preserving reproductive function.Methods:A case involving orthotopic detaenial sigmoid neobladder and preservation of reproductive function was retrospectively analyzed.Relevant literature was reviewed to consolidate clinical experiences.Results:The patient underwent transurethral prostatic plasma resection in addition to laparoscopic radical cystectomy and orthotopic detaenial sigmoid neobladder reconstruction.The surgery included capsular preservation of the prostate and bilateral seminal vesicles.Postoperative follow-up over 10 months showed no tumor metastasis.Postoperative examinations indicated satisfactory urinary and sexual function.Conclusion:With rigorous preoperative screening,this surgical technique significantly enhances the quality of life for male bladder cancer patients desiring to retain reproductive function.However,large-scale randomized controlled trials and long-term follow-up are necessary to further substantiate these findings.

关 键 词：膀胱恶性肿瘤 全去带乙状结肠原位新膀胱术 生殖功能 腹腔镜 

分 类 号：R737.14[医药卫生—肿瘤] R699.5[医药卫生—临床医学]