大脑后动脉伴发胚胎型改变与急性后循环脑梗死严重程度的关系  

Association of Embryonal Changes in Posterior Cerebral Artery with Severity of Acute Posterior Circulation Cerebral Infarction

作　　者：廖磊[1] 李明浩[1] 张辉[1] LIAO Lei;LI Minghao;ZHANG Hui(Department of Neurology,Nanyang Second People’s Hospital,Nanyang 473000,China)

机构地区：[1]南阳市第二人民医院神经内科,河南南阳473000

出　　处：《河南医学研究》2024年第20期3725-3728,共4页Henan Medical Research

基　　金：河南省医学科技攻关计划(LHGJ20191469)。

摘　　要：目的 探讨分析胚胎型大脑后动脉(FTP)改变与急性后循环脑梗死严重程度的关系。方法 选取南阳市第二人民医院2021年7月至2022年7月收治的96例急性后循环脑梗死患者,根据磁共振血管造影术结果,将患者分为非FTP组56例和FTP组40例,其中完全型FTP(cFTP)24例、部分型FTP(pFTP)16例。比较患者临床资料、梗死分布和后循环血管形态的情况,采用美国国立卫生研究院卒中量表(NIHSS)评估梗死严重程度,轻度梗死23例、中度梗死45例、重度梗死28例。采用多因素logistic回归分析FTP与急性后循环脑梗死严重程度的关系。结果 非FTP组和FTP组临床资料差异无统计学意义(P>0.05)。cFTP组和pFTP组大脑前动脉供血区、大脑中动脉供血区、大脑后动脉供血区、椎基底动脉供血区梗死和颅内段左椎动脉狭窄、颅内段右椎动脉狭窄、基底动脉弯曲凸向血管形态比较,差异无统计学意义(P>0.05)。中重度梗死组患者糖尿病、pFTP、cFTP占比高于轻度梗死组(P<0.05)。多因素logistic回归分析,结果显示,大脑中动脉供血区梗死、cFTP、pFTP是急性后循环脑梗死严重程度的独立危险因素(OR>1,P<0.05)。结论 FTP、梗死分布与急性后循环脑梗死严重程度密切相关,了解大脑后动脉伴发胚胎性改变情况及梗死分布情况对于脑梗死病情评估具有重要参考价值。Objective To investigate the relationship between the changes of fetal type posterior cerebral artery(FTP)and the severity of acute posterior circulation cerebral infarction.Methods A total of 96 patients with acute posterior circulation cerebral infarction admitted to Nanyang Second People’s Hospital from July 2021 to July 2022 were selected.According to the results of magnetic resonance angiography,the patients were divided into non-FTP group(56 cases)and FTP group(40 cases),in which 24 cases complete FTP(cFTP)and 16 cases partial FTP(pFTP).Clinical data,infarct distribution and posterior circulation vessel morphology were compared.The severity of infarction was assessed by the National Institutes of Health stroke scale(NIHSS).There were 23 cases of mild infarction,45 cases of moderate infarction and 28 cases of severe infarction.Then multivariate logistic regression was used to analyze the relationship between the posterior cerebral artery accompanying embryonic changes and the severity of acute posterior circulation cerebral infarction.Results There was no difference in clinical data between non-FTP group and FTP group(P>0.05).There were no differences between cFTP group and pFTP group in the anterior cerebral artery,middle cerebral artery,posterior cerebral artery and vertebrobasilar artery infarction,left vertebral artery stenosis,right vertebral artery stenosis,and basilar artery curvature and convex vascular morphology(P>0.05).The proportion of diabetes,pFTP and cFTP in moderate and severe infarction group was higher than that in mild infarction group(P<0.05).Multivariate logistic regression analysis showed that middle cerebral artery infarction,cFTP and pFTP were independent risk factors for the severity of acute posterior circulation cerebral infarction(OR>1,P<0.05).Conclusion The accompanying embryonic changes of the posterior cerebral artery and the distribution of infarction are closely related to the severity of acute posterior circulation cerebral infarction.Understanding the accompanying embryon

关 键 词：大脑后动脉伴发胚胎型改变 后循环脑梗死 梗死程度 

分 类 号：R743.3[医药卫生—神经病学与精神病学]