手术治疗前段巨眼合并白内障:病例报道和文献综述  

Cataract surgery in a patient with anterior megalophthalmos:a case report and literature review

作　　者：陈晓云(综述)[1] 黄圣松(审校)[1] CHEN Xiaoyun;HUANG Shengsong(State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou 510060,China)

机构地区：[1]中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州510060

出　　处：《眼科学报》2024年第9期454-461,F0002,共9页Eye Science

基　　金：广东省自然科学基金(2023A1515030108);广州市科技计划市校(院)联合资助项目(SL2024A03J00)。

摘　　要：前段巨眼(anterior megalophthalmos,AM)是一种罕见的双侧非进展性先天性眼前段增大疾病,表现为大角膜(直径≥12.5 mm)、前房极深、角膜厚度正常或轻中度变薄和睫状环扩大等。并发性白内障以及晶状体脱位是导致AM视力下降的主要原因。然而,解剖结构的异常使AM白内障手术具有很大的挑战性。文章报道了一例AM合并白内障的48岁男性患者,成功为其行手法小切口白内障摘除联合人工晶状体(intraocular lens,IOL)一期植入术,患者术后视力恢复良好,IOL位置居中,未出现较大的屈光误差。对该典型AM病例的临床特点以及手术难点的回顾总结,有助于加深广大眼科临床工作者对该疾病的认识。Anterior megalophthalmos is a rare congenital enlargement of the anterior segment,characterized by bilateral nonprogressive megalocornea(diameter ≥12.5 mm),extremely deep anterior chamber,normal or moderate thinning of the cornea,and elongation of the ciliary ring.Cataract and lens dislocation are the main causes of decreased vision in patients with AM.However,cataract surgery on patients with AM are challenging due to the anatomical abnormalities.This case reports a 48-year-old male patient diagnosed with AM and cataract,who successfully underwent a manual small incision cataract extraction combined with intraocular lens implantation.Finally,our patient showed a good visual outcome with a well centered IOL and without obvious refractive error.In this typical AM case,we reviewed and summarized the clinical characteristics and the challenges of surgical treatment so that other ophthalmologists can learn about this disease.

关 键 词：前段巨眼 大角膜 白内障手术 人工晶状体计算 人工晶状体脱位 

分 类 号：R772.23[医药卫生—眼科] R776.1[医药卫生—临床医学]