结直肠癌患者术后住院时间延长影响因素的Meta分析  

Influencing factors for prolonged postoperative hospital stay in patients with colorectal cancer:A Meta-analysis

作　　者：杨朔 魏花萍[2,5] 张云娇 关浩然 靳修 李宁[4,5] 孙国涛[5] Yang Shuo;Wei Huaping;Zhang Yunjiao;Guan Haoran;Jin Xiu;Li Ning;Sun Guotao(School of Nursing,Gansu University of Chinese Medicine,Lanzhou 730030,China;Outpatient Department,The First Hospital of Lanzhou University,Lanzhou 730000,China;Department of Cardiology,The First Hospital of Lanzhou University,Lanzhou 730000,China;Department of Anesthesia and Surgery,The First Hospital of Lanzhou University,Lanzhou 730000,China;School of Nursing,Lanzhou University,Lanzhou 730011,China)

机构地区：[1]甘肃中医药大学护理学院,甘肃兰州730030 [2]兰州大学第一医院门诊部,甘肃兰州730000 [3]兰州大学第一医院心内科,甘肃兰州730000 [4]兰州大学第一医院麻醉手术科,甘肃兰州730000 [5]兰州大学护理学院,甘肃兰州730011

出　　处：《兰州大学学报（医学版）》2024年第9期60-69,共10页Journal of Lanzhou University（Medical Sciences）

基　　金：甘肃省自然科学基金资助项目(23JRRA0934,23JRRA0936);兰州市城关区科技计划资助项目(XK-0301-225);兰州大学护理学院科研资助项目(LZUSON202010)。

摘　　要：目的通过Meta分析明确结直肠癌患者术后住院时间延长的影响因素。方法计算机检索中、英文数据库,从建库至2023年7月有关结直肠癌患者术后住院时间延长影响因素的所有文献及纳入文献的参考文献,由2名评价人员按照纳入、排除标准独立筛选文献、提取资料、评价文献质量。采用Review Manager 5.4软件对资料进行Meta分析。结果共纳入18篇文献,其中,队列研究7篇、病例对照研究1篇、横断面研究10篇,术后住院时间延长组10663例,术后住院时间未延长组32717例。男性(OR=1.14)、高龄(OR=1.74)、美国麻醉医师协会分级≥3级(OR=1.91)、糖尿病(OR=1.49)、高血压(OR=1.51)、心血管疾病(OR=1.82)、肺疾病(OR=1.71)、肾疾病(OR=1.75)、慢性阻塞性肺病(OR=2.74)、手术时长≥3 h(OR=1.65)、开腹手术(OR=3.35)、术中输血(OR=2.06)、肠造口术(OR=2.67)和术后并发症(OR=7.95)均为患者术后住院时间延长的危险因素。结论临床医护人员可根据危险因素识别术后住院时间延长高危患者,早期采取干预措施,改善患者临床预后。Objective To determine the factors that contribute to extended hospital stays following colorectal cancer surgery via a Meta-analysis.Methods Chinese and English databases were searched by computer.All the literatures from the establishment of the databases to July 2023 related to the influencing factors of prolonged hospitalization of patients with colorectal cancer and the references of the included literatures were screened,data extracted,and literature quality evaluated by two reviewers independently according to the relevant inclusion and exclusion standards.Review Manager 5.4 software was used to analyze the data.Results A total of 18 studies were included:7 cohort studies,1 case-control study,and 10 cross-sectional studies.There were 10663 cases with a prolonged postoperative hospital stay and 32717 without.Male(OR=1.14),advanced age(OR=1.74),American Society of Anesthesiologists physical status classification system≥3(OR=1.91),diabetes(OR=1.49),hypertension(OR=1.51),ardiovascular disease(OR=1.82),pulmonary disease(OR=1.71),renal disease(OR=1.75),chronic obstructive pulmonary(OR=2.74),operation time≥3 h(OR=1.65),open surgery(OR=3.35),intraoperative blood transfusion(OR=2.06),enterostomy(OR=2.67)and postoperative complications(OR=7.95)were all risk factors for prolonging postoperative hospital stay.Conclusion Clinical medical staff can identify high-risk patients with prolonged hospitalization according to the above risk factors,and thus take early intervention measures to improve the clinical prognosis of patients.

关 键 词：加速康复外科 结直肠癌 住院时间 延长 影响因素 META分析 

分 类 号：R735.3[医药卫生—肿瘤]