眼动追踪技术在神经退行性疾病中的应用研究进展  

Research progress on the application of eye tracking technology in neurodegenerative diseases

作　　者：王烽 赖江峰[1] 蓝诚红[1] 刘清云[1] 邵毅 WANG Feng;LAI Jiangfeng;LAN Chenghong;LIU Qingyun;SHAO Yi(Department of Ophthalmology,Meizhou Pepole’s Hospital,Meizhou 514000,Guangdong Province,China;Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,National Clinical Research Center for Eye Disease,Shanghai 200080,China)

机构地区：[1]梅州市人民医院眼科,广东省梅州市514000 [2]上海交通大学医学院附属第一人民医院眼科,国家眼部疾病临床医学研究中心,上海市200080

出　　处：《眼科新进展》2024年第11期908-913,共6页Recent Advances in Ophthalmology

基　　金：国家自然科学基金(编号:82160195);中央引导地方科技发展资金(编号:20211ZDG02003);江西省重点研发项目(编号:20181BBG700004,20203BBG73059);广东省梅州市人民医院科研培育项目(编号:PY-C2021060)。

摘　　要：在许多神经退行性疾病中,眼球运动均会受到干扰,并且是影响神经退行性疾病的常见和早期特征,表征眼球运动对诊断很重要,有助于跟踪疾病进展和对治疗的反应。近年来,眼动追踪技术已被应用于神经退行性疾病患者的认知功能评估,相较于传统的认知评估方法,该技术具有更高的时间和空间分辨率的灵敏定量。眼动追踪数据证实,执行功能障碍在帕金森病和肌萎缩侧索硬化症中很常见,而阿尔茨海默病和多发性硬化症的特点是注意力缺陷,使用眼动追踪评估癫痫认知功能的研究仍处于早期阶段,但这种方法已显示出优势。现就眼动追踪技术在神经退行性疾病中的应用作一综述。In many neurodegenerative diseases,eye movement is disrupted,which is a common and early characteristic of neurodegenerative diseases.Characterizing eye movement is important for the diagnosis of neurodegenerative diseases,helping to track disease progression and response to treatment.In recent years,eye tracking technology has been applied to the assessment of cognitive function in patients with neurodegenerative diseases.Compared to traditional cognitive assessment methods,the technology has higher temporal and spatial resolution for sensitive quantification.Eye tracking data confirms that executive dysfunction is common in Parkinson’s disease and amyotrophic lateral sclerosis,while attention deficit is a characteristic of Alzheimer’s disease and multiple sclerosis.Research using eye tracking to evaluate the cognitive function of epilepsy patients is still in its early stages,but this method has shown advantages.In this article,the application of eye tracking technology in neurodegenerative diseases is reviewed.

关 键 词：眼动追踪 神经退行性疾病 肌萎缩侧索硬化症 阿尔茨海默病 帕金森病 多发性硬化症 癫痫 

分 类 号：R770.43[医药卫生—眼科]