应用OCTA评估高血压患者视网膜改变的研究进展  

Progress in the application of OCTA to assess retinal changes in hypertensive patients

作　　者：燕鹏 谷愉 孙佳 赵炆秋 李园平 杨冬妮[2] Yan Peng;Gu Yu;Sun Jia;Zhao Wenqiu;Li Yuanping;Yang Dongni(Chengde Medical College,Chengde 067000,China;Department of Ophthalmology,the First Hospital of Qinhuangdao,Qinhuangdao 066000,China;Department of Ophthalmology,Yanan University Affiliated Hospital,Yanan 716000,China)

机构地区：[1]承德医学院,067000 [2]秦皇岛市第一医院眼科,066000 [3]延安大学附属医院,716000

出　　处：《临床眼科杂志》2024年第5期465-469,共5页Journal of Clinical Ophthalmology

摘　　要：高血压视网膜改变是指由急性或慢性血压升高所引起的视网膜变化。持续的血压升高会导致视网膜的结构和微循环发生改变,继而出现视网膜的缺血、缺氧,最终引起视功能的损害[1]。由于视网膜血管与体内其他血管具有相似的胚胎起源,这种视网膜的改变也被认为是高血压损害其他靶器官的重要标志[2-3]。相干光层析血管成像术(OCTA)是近年来迅速发展并广泛应用于临床的一种非侵入性、高分辨率、可重复的实时光学成像技术,其能够无创地对视网膜微循环进行成像,并通过其内置的软件或其他方式将图像量化为数据,继而评估视网膜微循环的状态,为眼底疾病的探究提供了新的思路。Hypertensive retinal changes are retinal changes caused by acute or chronic elevation of blood pressure.Persistent elevation of blood pressure leads to structural and microcirculatory changes in the retina,followed by ischemia and hypoxia of the retina,which ultimately causes damage to visual function.Because retinal blood vessels have similar embryonic origins to other blood vessels in the body,such retinal changes are also considered to be an important marker of hypertensive damage to other target organs.The optical coherence tomography flow imaging is a non-invasive,highresolution,reproducible,real-time optical imaging technique that has been rapidly developed and widely used in clinical practice in recent years.Its ability to noninvasive image the retinal microcirculation and quantify the images into data through its built-in software or other means,and subsequently assess the state of the retinal microcirculation,provides new ideas for the investigation of fundus diseases.

关 键 词：高血压视网膜改变 黄斑区 视盘区 微循环 相干光层析血管成像术 

分 类 号：R774.1[医药卫生—眼科] R544.1[医药卫生—临床医学]