管状胃-食管吻合术联合胸腔镜食管癌切除术治疗食管癌的效果及对胃肠功能的影响  

Effect of tubular gastroesophageal anastomosis combined with thoracoscopic esophageal cancer resection in the treatment of esophageal cancer and its influence on gastrointestinal function

作　　者：孙志红[1] 葛鹏[1] 陈鑫[1] SUN Zhihong;GE Peng;CHEN Xin(the Second Affiliated Hospital of Xi'an Medical University,Xi'an 710038,China)

机构地区：[1]西安医学院第二附属医院,陕西西安710038

出　　处：《临床医学研究与实践》2024年第30期45-48,共4页Clinical Research and Practice

摘　　要：目的探讨分析管状胃-食管吻合术联合胸腔镜食管癌切除术治疗食管癌的效果及对胃肠功能的影响。方法选取2021年1月至2023年1月我院收治的70例食管癌患者为研究对象,以随机数字表法将其分为对照组和观察组,各35例。两组均实施胸腔镜食管癌切除术,对照组联合应用全胃代食管吻合术重建消化道,观察组联合应用管状胃-食管吻合术重建消化道。比较两组的治疗效果。结果观察组的手术时间、腹腔引流时间及住院时间短于对照组,术中出血量少于对照组(P<0.05)。术后,观察组的胸胃静息压、蠕动收缩压及蠕动频率高于对照组(P<0.05)。术后,观察组的肺活量(VC)、用力肺活量(FVC)及第1秒用力呼气容积(FEV_(1))/FVC高于对照组(P<0.05)。术后,观察组的皮质醇(Cor)及β-内啡肽(β-EP)水平低于对照组(P<0.05)。结论管状胃-食管吻合术联合胸腔镜食管癌切除术治疗食管癌能提高手术效果,缩短手术时间和术后恢复时间,减少术中出血量,减轻对胃肠功能、肺功能造成的影响,下调机体应激反应,值得推广。Objective To investigate and analyze the effect of tubular gastroesophageal anastomosis combined with thoracoscopic esophageal cancer resection in the treatment of esophageal cancer and its influence on gastrointestinal function.Methods A total of 70 patients with esophageal cancer admitted in our hospital from January 2021 to January 2023 were selected as the research objects.The patients were divided into control group and observation group by random number table method,with 35 cases in each group.Thoracoscopic esophageal cancer resection was performed in both groups,the control group was combined with total gastroesophageal anastomosis to reconstruct the digestive tract,and the observation group was combined with tubular gastroesophageal anastomosis to reconstruct the digestive tract.The therapeutic effects of the two groups were compared.Results The operation time,abdominal drainage time and hospitalization time of the observation group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group(P<0.05).After operation,the chest and stomach resting pressure,peristaltic systolic pressure and peristaltic frequency in the observation group were higher than those in the control group(P<0.05).After operation,the vital capacity(VC),forced vital capacity(FVC)and forced expiratory volume in the first second(FEV_(1))/FVC in the observation group were higher than those in the control group(P<0.05).After operation,the levels of cortisol(Cor)andβ-endorphin(β-EP)in the observation group were lower than those in the control group(P<0.05).Conclusion Tubular gastroesophageal anastomosis combined with thoracoscopic esophageal cancer resection in the treatment of esophageal cancer can improve the surgical effect,shorten the operation time and postoperative recovery time,reduce the amount of intraoperative blood loss,relieve the impact on gastrointestinal function and lung function,and down-regulate the body's stress response,which is worthy of promotion.

关 键 词：管状胃-食管吻合术 胸腔镜食管癌切除术 食管癌 胃肠功能 肺功能 

分 类 号：R735.1[医药卫生—肿瘤]