急性髓系白血病异基因造血干细胞移植后阿萨希毛孢子菌感染2例报告及文献复习  

Infection of Aspergillus fumigatus after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia:2 cases report and literature review

作　　者：赵玮 陈曼 赵艳丽 Zhao Wei;Chen Man;Zhao Yanli(Department of Transplantation,Beijing Ludaopei Hospital,Beijing 100176,China;Department of Laboratory Medicine,Hebei Yanda Ludaopei Hospital,Langfang 065201,China)

机构地区：[1]北京陆道培医院移植科,北京100176 [2]河北燕达陆道培医院检验科,廊坊065201

出　　处：《中华血液学杂志》2024年第9期848-850,共3页Chinese Journal of Hematology

摘　　要：由于造血干细胞移植后患者免疫力低下,不常见或罕见的酵母菌感染呈上升趋势。对由这些病原体引起的复杂、多学科的感染管理采取恰当的治疗对于优化患者预后至关重要。本文报告了2例血液病患者合并罕见酵母菌阿萨希毛孢子菌感染的诊疗过程,提示我们应及时进行多脏器筛查有无全身播散性感染,早治疗及联合用药可改善预后。Rare yeast infections have been slowly increasing,given the increasing numbers of patients who are immunocompromised after hematopoietic stem cell transplantation.A considered approach to the complex,multidisciplinary management of infections that are caused by these pathogens is essential to optimize patient outcomes.We reported the management of two patients with combined rare yeast Trichosporon asahii infections,that suggested we should perform timely multivisceral screening for systemic dissemination of infection,and early treatment and combination of medications may improve prognosis.

关 键 词：阿萨希毛孢子菌 急性髓系白血病 免疫力低下 血液病患者 感染管理 联合用药 多脏器 诊疗过程 

分 类 号：R733.71[医药卫生—肿瘤]