改良无抽搐电休克治疗迟发性综合征3例  

Improvement of tardive syndrome in three cases treated with modified electroconvulsive therapy

作　　者：黄冰洁 季云飞 蒲城城[1] Huang Bingjie;Ji Yunfei;Pu Chengcheng(Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100191,China)

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100191

出　　处：《中华精神科杂志》2024年第10期682-684,共3页Chinese Journal of Psychiatry

摘　　要：迟发性综合征(tardive syndrome,TS)是长期使用多巴胺受体拮抗剂引起的运动障碍,是精神科医生面临的一大临床难题。降低抗精神病药剂量、更换抗精神病药、联用囊泡单胺转运体-2抑制剂等常难以兼顾精神症状和运动症状的控制。同时TS可分为迟发性肌张力障碍、迟发性多动等不同亚型,治疗原则存在差异。本文报告了改良无抽搐电休克治疗对3个不同亚型TS病例的改善情况,以期对TS的治疗提供新的临床思路。Tardive syndrome(TS)is a movement disorder caused by long-term treatment with dopamine-blocking agents,posing a significant clinical challenge for psychiatrists.Lowering the antipsychotic dosage,switching antipsychotics,and combining a vesicular monoamine transporter-2 inhibitor often fail to adequately control both psychiatric and motor symptoms.Additionally,TS can manifest in different subtypes,such as tardive dystonia and tardive hyperkinesia,each requiring distinct treatment approaches.This article reports on the improvement observed in three cases of different TS subtypes treated with modified electroconvulsive therapy,aiming to provide new clinical insights for treating TS.

关 键 词：电休克 方法 改良无抽搐电休克治疗 迟发性综合征 运动障碍 药物性 精神障碍 

分 类 号：R749.054[医药卫生—神经病学与精神病学]