宫颈腺上皮形态学评分在宫颈液基细胞学检查中的应用价值  

Application value of cervical glandular epithelial morphological score in cervical liquid-based cytology examination

作　　者：陈裕章 梁储财 梁少姬[1] 李文成[1] CHEN Yuzhang;LIANG Chucai;LIANG Shaoji;LI Wencheng(Department of Pathology,Zhaoqing Second People’s Hospital,Zhaoqing 526060,Guangdong,China)

机构地区：[1]肇庆市第二人民医院病理科,广东肇庆5260600

出　　处：《癌症进展》2024年第18期2040-2043,共4页Oncology Progress

基　　金：2022年肇庆市科技创新指导类项目(2022040314028)。

摘　　要：目的探讨宫颈腺上皮形态学评分在宫颈液基细胞学检查中的应用价值。方法选取50例行宫颈液基细胞学检查和病理检查者,根据宫颈腺上皮细胞形态学改变情况进行评分,以宫颈液基细胞学检查初诊结果为评分前结果,应用评分标准辅助判读后的结果为评分后结果。以病理检查结果为金标准,分析评分前和评分后宫颈液基细胞学检查对宫颈腺上皮病变的诊断价值,并分析其对不同组织学类型宫颈腺上皮病变的诊断结果。结果评分后宫颈液基细胞学检查诊断宫颈腺上皮病变的灵敏度、特异度、准确度分别为93.33%、82.86%、86.00%,分别高于评分前宫颈液基细胞学检查的73.33%、54.29%、60.00%。评分前宫颈液基细胞学检查诊断宫颈腺上皮病变真阳性11例、漏诊4例,9例患者组织学类型诊断准确,阳性患者中诊断准确度为60.00%(9/15)。评分后宫颈液基细胞学检查诊断宫颈腺上皮病变真阳性14例、漏诊1例,10例患者组织学类型诊断准确,阳性患者中诊断准确度为66.67%(10/15)。结论在宫颈液基细胞学检查中应用宫颈腺上皮形态学评分,可提高宫颈腺上皮病变的诊断价值。Objective To explore the application value of cervical glandular epithelial morphological score in cervical liquid-based cytology examination.Method Fifty subjects who underwent cervical fluid-based cytology and pathological examinations were selected and scored according to the morphological changes of cervical glandular epithelial cells.The results of initial cervical fluid-based cytology examination were taken as the pre-scoring results,and the results after the application of scoring criteria to assist interpretation were taken as the post-scoring results.Using the results of pathological examination as the gold standard,the diagnostic value of pre-scoring and post-scoring cervical liquid-based cytology examinations for cervical glandular epithelial lesions were analyzed,and the diagnostic results of pre-scoring and post-scoring cervical liquid-based cytology examinations for different histological types of cervical glandular epithelial lesions were also analyzed.Result The sensitivity,specificity and accuracy of post-scoring cervical liquid-based cytology examination in diagnosing cervical glandular epithelial lesions were 93.33%,82.86%and 86.00%,respectively,higher than 73.33%,54.29%and 60.00%of pre-scoring cervical liquid-based cytology examination.There were 11 true positive and 4 missed cases of cervical glandular epithelial lesions diagnosed by pre-scoring cervical fluid-based cytology examination,histological types were diagnosed accurately in 9 patients,the diagnostic accuracy was 60.00%(9/15)in positive patients.There were 14 true positive and 1 missed cases of cervical glandular epithelial lesions diagnosed by postscoring cervical fluid-based cytology examination,histological types were diagnosed accurately in 10 patients,the diagnostic accuracy was 66.67%(10/15)in positive patients.Conclusion The application of cervical glandular epithelial morphological score in cervical liquid-based cytology examination can improve the diagnostic value of cervical glandular epithelial lesions.

关 键 词：宫颈液基细胞学检查 宫颈腺上皮病变 宫颈腺上皮形态学评分 诊断价值 

分 类 号：R737.33[医药卫生—肿瘤]