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作 者:王飞 郭赜铭 李纪宾 曹巍 董学思 王晨冉 李霓 Wang Fei;Guo Zeming;Li Jibin;Cao Wei;Dong Xuesi;Wang Chenran;Li Ni(Office of Cancer Screening,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)
机构地区:[1]国家癌症中心/国家恶性肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院癌症早诊早治办公室,北京100021
出 处:《肿瘤综合治疗电子杂志》2024年第4期14-19,共6页Journal of Multidisciplinary Cancer Management(Electronic Version)
基 金:国家自然科学基金面上项目(82273722);国家自然科学基金青年项目(82204143)。
摘 要:肺癌目前是我国疾病负担最重的恶性肿瘤之一,对经济和社会造成了显著的影响。肺癌的发病率和死亡率在我国不同地区存在显著差异,这些差异与多种因素密切相关,包括环境污染、职业暴露、生活习惯和遗传易感性等。本文对目前我国肺癌高发区的防治研究进展和面临的挑战进行了总结。结果发现,宣威市和个旧市由于室内煤烟暴露等显著增加了当地居民的肺癌风险。东北地区则由于长期依赖燃煤取暖以及工业化进程加快,导致肺癌的发病率显著上升。此外,吸烟习惯和遗传易感性等因素也在不同地区的肺癌发生中发挥了重要作用。针对这些高发区的防治研究已经取得了一些进展,包括环境治理、职业健康保护、公众健康教育和早期筛查等方面的工作。Lung cancer is currently one of the malignancies with the heaviest disease burden in China,exerting a significant impact on the economy and society.The incidence and mortality rates of lung cancer vary significantly across different regions of the country,and these disparities are closely linked to multiple factors,including environmental pollution,occupational exposure,lifestyle habits,and genetic susceptibility.This paper summarized the current progress and challenges in the prevention and treatment of lung cancer in high-risk areas in China.The results showed that the indoor coal smoke exposure was significantly increased the risk of lung cancer in Xuanwei City and Gejiu City.In northeast China,the long-term reliance on coal for heating and the rapid pace of industrialization have led to a marked rise in lung cancer incidence.Additionally,smoking habits and genetic susceptibility have also played a critical role in the occurrence of lung cancer in different regions.Research on prevention and treatment in these high-risk areas has made some progress,including efforts in environmental management,occupational health protection,public health education,and early screening.
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