保留外中耳结构的颈静脉孔区副神经节瘤手术探索(附2例报道)  

Exploration of technique for preservation of external-middle ear structure in surgery of jugular foramen paraganglioma(appended 2 case reports)

作　　者：宋勇莉 朱正茹 胡健 潘洋洋 邱建华 查定军 SONG Yongli;ZHU Zhengru;HU Jian;PAN Yangyang;QIU Jianhua;ZHA Dingjun(Department of Otolaryngology Head and Neck Surgery,First Affiliated Hospital of Air Force Medical University,Xi'an,710032,China)

机构地区：[1]空军军医大学第一附属医院耳鼻咽喉头颈外科,西安710032

出　　处：《临床耳鼻咽喉头颈外科杂志》2024年第9期818-822,829,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的探讨对经典颞下窝A型入路进行技术改良,保留外中耳结构,对于颈静脉孔区副神经节瘤手术治疗的可行性及效果。方法回顾性分析2例接受经迷路下经乳突-上颈部联合入路手术治疗的颈静脉孔区副神经节瘤患者的病例资料,分析患者颈静脉孔区副神经节瘤病变的临床特征,肿瘤切除程度,术后面神经功能及听力保留情况,及术后并发症的发生等。结果2例患者均为女性,术后病理均确定为副神经节瘤。患者肿瘤分期分别为:病例1 C2De1,病例2 C1De1;2例患者肿瘤均得到完全切除,术后病例1发生感染,遗留鼓膜穿孔及混合性耳聋。病例2术后出现左侧轻度面瘫(Ⅱ级),予以对症治疗后恢复。随访半年均未见肿瘤残留或复发。结论对于部分颈静脉孔区副神经节瘤采用迷路下经乳突-上颈部联合入路进行手术治疗,可实现切除肿瘤的同时保留外中耳结构和功能,从而提高患者的生活质量。该术式适用于病变局限于颈静脉孔区,不累及或仅累及颈内动脉垂直段(C1或C2),不伴有明显听力下降的副神经节瘤患者。Objective To investigate the feasibility and effect of the modified surgery of the classic infratemporal fossa type A approach for the surgical treatment of jugular foramen paraganglioma with preservation of the external and middle ear structures.Methods The medical data of 2 patients with jugular foraminal paraganglioma treated by sublabyrinthic-transmastoid approach were retrospectively analyzed.The clinical feature,degree of tumor resection,postoperative facial nerve function and hearing retention,and the incidence of postoperative complications were evaluated.Results Two patients were both female,and were pathologically confirmed as paraganglioma.The tumor of case 1 was staged as C2De1,and case 2 as C1De1.Tumors were completely resected in both patients.Case 1 suffered infection after surgery,with residual tympanic membrane perforation and mixed deafness.Case 2 developed mild facial paralysis(gradeⅡ)after surgery,and recovered after symptomatic treatment.There was no tumor residue or recurrence during half a year of follow-up.Conclusion Surgical treatment of certain paragangliomas in the jugular foramen with a combined sublabyrinthic-transmastoid and upper neck approach might achieve both complete resection of the tumor and preserving the structure and function of the outer-middle ear.This procedure is suitable for paragangliomas restricted in the jugular foramen area,with no or limited involvement of the internal carotid artery(C1 or C2),and with no or mild hearing loss.

关 键 词：颈静脉孔区 副神经节瘤 手术治疗 面神经 听力保留 迷路下入路 

分 类 号：R739.4[医药卫生—肿瘤]