剪切波黏弹性成像鉴别肺周围型炎性肿块与恶性肿瘤  

Shear wave viscoelastography for differentiating lung peripheral inflammatory masses and malignant tumors

作　　者：韦季伶 李春莹 袁晗 陈姮霏 高泳[1] 廖新红[1] WEI Jiling;LI Chunying;YUAN Han;CHEN Hengfei;GAO Yong;LIAO Xinhong(Department of Ultrasound,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院超声科,广西南宁530021

出　　处：《中国医学影像技术》2024年第10期1524-1528,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察剪切波黏弹性成像(SWV)鉴别肺周围型炎性肿块与恶性肿瘤的价值。方法前瞻性对70例周围型肺肿块患者行常规灰阶超声及SWV,根据病理结果将其分为恶性组(n=42)及炎性组(n=28);比较组间临床及超声资料,包括病灶最大径、平均杨氏模量(E_(mean))、平均黏性值(V_(mean))及平均频散斜率(D_(mean));针对组间差异有统计学意义的超声参数绘制受试者工作特征曲线,计算曲线下面积(AUC),评估其鉴别肺周围型炎性肿块与恶性肿瘤的效能。结果恶性组病灶最大径及E_(mean)均高于,而V_(mean)及D_(mean)均低于炎性组(P均<0.05)。以病灶V_(mean)及D_(mean)鉴别肺周围型炎性肿块与恶性肿瘤的效能中等/良好(AUC=0.843、0.866),且均优于常规超声及病灶E_(mean)(AUC=0.673、0.685)(P均<0.05)。联合病灶E_(mean)、V_(mean)及D_(mean)鉴别肺周围型炎性肿块与恶性肿瘤的效能良好,AUC=0.874。结论SWV黏性参数可有效鉴别肺周围型炎性肿块与恶性肿瘤。Objective To observe the value of shear wave viscoelastography(SWV)for differentiating lung peripheral inflammatory masses and malignant tumors.Methods Conventional gray-scale ultrasound and SWV were prospectively performed in 70 patients with lung peripheral inflammatory mass or malignant tumor.The patients were divided into malignant group(n=42)and inflammatory group(n=28)according to pathological results.Clinical and ultrasonic data,including the maximum diameter of lesions,the_(mean) Young's modulus(E_(mean)),mean viscosity(V_(mean)),and_(mean) dispersion slope(D_(mean))were compared between groups.Receiver operating characteristic curves of ultrasonic parameters being significantly different between groups were drawn,and area under the curves(AUCs)were calculated to evaluate the efficacy of each parameter for differentiating lung peripheral inflammatory mass or malignant tumor.Results In malignant group,the maximum diameter and E_(mean) of lesions were both higher,while V_(mean) and D_(mean) of lesions were both lower than those in inflammatory group(all P<0.05).V_(mean) and D_(mean) of lesions had moderately/good efficacy for differentiating lung peripheral inflammatory mass or malignant tumor(AUC=0.843,0.866),both better than that of conventional ultrasound and E_(mean)(AUC=0.673,0.685)(all P<0.05).The combination of E_(mean),V_(mean) and D_(mean) had good efficacy for differentiating lung peripheral inflammatory masses and malignant tumors,with AUC of 0.874.Conclusion The viscous parameters of SWV could effectively differentiating lung peripheral inflammatory masses and malignant tumors.

关 键 词：肺肿瘤 肺炎 超声检查 诊断 鉴别 前瞻性研究 

分 类 号：R734.2[医药卫生—肿瘤] R445.1[医药卫生—临床医学]