术中超声在脑胶质瘤切除术中应用价值的Meta分析  

Meta-Analysis about the Value of Intraoperative Ultrasound in the Glioma Resection Surgery

作　　者：方梦茹 韩丽 王璐 卢漫[2] Fang Mengru;Han Li;Wang Lu;Lu Man(School of Medical and Life Sciences,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,Sichuan,China;Ultrasound Medical Center,Sichuan Clinical Research Center for Cancer,Sichuan Cancer Hospital&Institute,Sichuan Cancer Center,Affliated Cancer Hospital of University of Electronic Science and Technology of China,Chengdu 610041,Sichuan,China)

机构地区：[1]成都中医药大学医学与生命科学学院,成都610000 [2]四川省肿瘤临床医学研究中心,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学附属肿瘤医院超声医学中心,成都610041

出　　处：《肿瘤预防与治疗》2024年第10期865-873,共9页Journal of Cancer Control And Treatment

基　　金：国家重点研发计划(编号:2019YFE0196700)。

摘　　要：目的:系统评价术中超声(intraoperative ultrasound,IOUS)引导脑胶质瘤切除的全切率、手术时间及预后。方法:在中国知网、万方、维普、中国生物医学文献数据库、PubMed、Web of Science、Embase、The Cochrane Library搜索关于IOUS在脑胶质瘤切除中应用的文献,检索时间为建库至2022年12月。由两名评价者独立对纳入文献进行严格评价和资料提取后,采用Review Manager 5.4软件进行Meta分析。结果:最终纳入16篇文献,共1573个病例。在全切率、手术时间、1年生存率和2年生存率方面,IOUS组与对照组的差异有统计学意义(RR=1.41,95%CI:1.27~1.56,P<0.001;SMD=-0.56,95%CI:-0.74~-0.38,P<0.001;RR=1.35,95%CI:1.19~1.53,P<0.001;RR=1.63,95%CI:1.34~2.00,P<0.001)。结论:IOUS引导脑胶质瘤切除术能提高全切率、缩短手术时间及提高1年生存率和2年生存率。Objective:To systematically evaluate the total resection rate and operation time of glioma resection surgery guided by intraoperative ultrasound(IOUS),and the prognosis of patients.Methods:The literature about the application of IOUS in the resection of glioma was searched from the databases including CNKI,Wan Fang,VIP,CBM,PubMed,Web of Science,Embase and the Cochrane Library from the establishment of the database to December 2022.After rigorous evaluation and data extraction by two evaluators independently,meta-analysis was conducted by Review Manager 5.4.Results:Sixteen articles with a total of 1,573 cases were included.In the total resection rate,surgical duration,1-year survival rate,and 2-year survival rate,there were statistically significant differences between the IOUS group and the control group(RR=1.41,95%CI:1.27~1.56,P<0.001;SMD=-0.56,95%CI:-0.74~-0.38,P<0.001;RR=1.35,95%CI:1.19~1.53,P<0.001;RR=1.63,95%CI:1.34~2.00,P<0.001).Conclusion:Glioma resection surgery guided by IOUS can improve the total resection rate,shorten the surgical duration,and improve the 1-and 2-year survival rates of the patients.

关 键 词：术中超声 脑胶质瘤 META分析 手术 引导 

分 类 号：R739.41[医药卫生—肿瘤]